Background Phenotypic presentations in young children with asthma are varied and might
contribute to differential responses to asthma controller medications. Methods The …

Rationale: Obesity is associated with increased asthma morbidity, lower drug responsiveness
to inhaled corticosteroids, and worse asthma control. However, most prior investigations …

Background Childhood asthma prevalence and morbidity varies among Latinos in the
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …

Rationale: Albuterol, a bronchodilator medication, is the first-line therapy for asthma worldwide.
There are significant racial/ethnic differences in albuterol drug response. Objectives: To …

BACKGROUND Obesity is associated with poor asthma control, increased asthma morbidity,
and decreased response to inhaled corticosteroids. We hypothesized that obesity would be …

Background Studies have suggested an association between frequent acetaminophen use
and asthma-related complications among children, leading some physicians to recommend …

Rationale: Adverse effects of exposures to ambient air pollution on lung function are well
documented, but evidence in racial/ethnic minority children is lacking. Objectives: To assess …

Background Inhaled corticosteroids (ICS) are the most widely prescribed and effective
medication to control asthma symptoms and exacerbations. However, many children still have …

Short-acting β 2 -adrenergic receptor agonists (SABAs) are the most commonly prescribed
asthma medications worldwide. Response to SABAs is measured as bronchodilator drug …

Background IgE is a key mediator of allergic inflammation, and its levels are frequently
increased in patients with allergic disorders. Objective We sought to identify genetic variants …