Identification of fluoxetine as a direct NLRP3 inhibitor to treat atrophic macular degeneration
M Ambati, I Apicella, S Wang… - Proceedings of the …, 2021 - National Acad Sciences
The atrophic form of age-related macular degeneration (dry AMD) affects nearly 200 million
people worldwide. There is no Food and Drug Administration (FDA)-approved therapy for …
people worldwide. There is no Food and Drug Administration (FDA)-approved therapy for …
Edmondson-Steiner grading increases the predictive efficiency of TNM staging for long-term survival of patients with hepatocellular carcinoma after curative resection
L Zhou, JA Rui, DX Ye, SB Wang, SG Chen… - World journal of surgery, 2008 - Springer
Background The 6th edition TNM staging (TNM-6) for hepatocellular carcinoma (HCC) has
been recommended. However, its superiority, in contrast to the previous 5th edition (TNM-5), …
been recommended. However, its superiority, in contrast to the previous 5th edition (TNM-5), …
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs
Detection of microbial products by multiprotein complexes known as inflammasomes is
pivotal to host defense against pathogens. Nucleotide-binding domain leucine-rich repeat (NLR) …
pivotal to host defense against pathogens. Nucleotide-binding domain leucine-rich repeat (NLR) …
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration
Alu retroelements propagate via retrotransposition by hijacking long interspersed nuclear
element-1 (L1) reverse transcriptase (RT) and endonuclease activities. Reverse transcription …
element-1 (L1) reverse transcriptase (RT) and endonuclease activities. Reverse transcription …
Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity
Long interspersed nuclear element-1 (L1)–mediated reverse transcription (RT) of Alu RNA
into cytoplasmic Alu complementary DNA (cDNA) has been implicated in retinal pigmented …
into cytoplasmic Alu complementary DNA (cDNA) has been implicated in retinal pigmented …
Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases
Y Xu, C Tian, SB Wang, WL Xie, Y Guo, J Zhang… - Autophagy, 2012 - Taylor & Francis
Macroautophagy is an important process for removing misfolded and aggregated protein in
cells, the dysfunction of which has been directly linked to an increasing number of …
cells, the dysfunction of which has been directly linked to an increasing number of …
Shape-controlled synthesis of one-dimensional α-MnO2 nanocrystals for organic detection and pollutant degradation
Shape control is an important technique for improving the quality and activity of nanomaterials.
Two types of one-dimensional manganese dioxide (MnO 2 ) nanocrystals with different …
Two types of one-dimensional manganese dioxide (MnO 2 ) nanocrystals with different …
Prognostic Value of ALT, AST, and AAR in Hepatocellular Carcinoma with B-Type Hepatitis-Associated Cirrhosis after Radical Hepatectomy.
L Zhou, SB Wang, SG Chen, Q Qu… - Clinical laboratory, 2018 - search.ebscohost.com
Background: Alanine aminotransferase (ALT), aspartate aminotransferase (AST), and AST
to ALT ratio (AAR) were shown to be associated with prognosis in some groups of …
to ALT ratio (AAR) were shown to be associated with prognosis in some groups of …
CCR3 monoclonal antibody inhibits airway eosinophilic inflammation and mucus overproduction in a mouse model of asthma1
H SHEN, F Xu, G ZHANG, S WANG… - Acta pharmacologica …, 2006 - Wiley Online Library
Aim: To explore the effect of a rat anti‐mouse CC‐chemokine receptor‐3 (CCR3) monoclonal
antibody (CCR3 mAb) on airway eosinophilia and mucus overproduction in asthmatic mice…
antibody (CCR3 mAb) on airway eosinophilia and mucus overproduction in asthmatic mice…
Edmondson-Steiner grade: A crucial predictor of recurrence and survival in hepatocellular carcinoma without microvascular invasio
L Zhou, JA Rui, WX Zhou, SB Wang, SG Chen… - Pathology-Research and …, 2017 - Elsevier
Background Microvascular invasion (MVI), an important pathologic parameter, has been
proven to be a powerful predictor of long-term prognosis in hepatocellular carcinoma (HCC). …
proven to be a powerful predictor of long-term prognosis in hepatocellular carcinoma (HCC). …