By dividing asymmetrically, stem cells can generate two daughter cells with distinct fates.
However, evidence is limited in mammalian systems for the selective apportioning of …

A decline in stem cell function impairs tissue regeneration during ageing, but the role of the
stem-cell-supporting niche in ageing is not well understood. The small intestine is …

The morphology and functionality of the epithelial lining differ along the intestinal tract, but
tissue renewal at all sites is driven by stem cells at the base of crypts 1 , 2 – 3 . Whether stem …

Smooth muscle is an essential component of the intestine, both to maintain its structure and
produce peristaltic and segmentation movements. However, very little is known about other …

Epithelial attachment to the basement membrane (BM) is essential for mammary gland
development, yet the exact roles of specific BM components remain unclear. Here, we show that …

N Fluoroquinuclidinium tetrafluoroborate (1b) has been prepared in excellent yield by “transfer
fluorination” of quinuclidine with 1 chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane …

Structural properties of the proton-exchanged forms of bis[(perfluoroalkyl)sulfonyl] imide (PFSI)
ionomer materials were investigated. The hydration and dehydration of samples …

A convenient one-pot method has been developed for the preparation of the easily
handledelectrophilic fluorinating agent N-fluoroquinuclidinium triflate from quinuclidine, lithiumtrifiate …

Bis(4-fluoro-1,4-diazoniabicyclo[2.2.2]oct-1-yl)-ethane and -propane tetratriflates (4, 5), and
1,1′-difluoro-4,4′-bipyridinium ditriflate (6) were prepared by solution-phase direct …

Background & Aims Microfold cells (M cells) are immunosurveillance epithelial cells located
in the Peyer’s patches (PPs) in the intestine and are responsible for monitoring and …