User profiles for Sharon Hassin-Baer
 | Sharon Hassin-BaerNeurologist, movement disorders specialist; director, Movement Disorders Institute, Sheba … Verified email at post.tau.ac.il Cited by 6939 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Background Genome-wide association studies (GWAS) in Parkinson's disease have increased
the scope of biological knowledge about the disease over the past decade. We aimed to …
the scope of biological knowledge about the disease over the past decade. We aimed to …
Novel PINK1 mutations in early‐onset parkinsonism
…, M Asahina, S Kobayashi, S Hassin‐Baer… - Annals of …, 2004 - Wiley Online Library
PINK1 was recently found to be associated with PARK6 as the causative gene. We performed
mutation analysis in eight inbred families whose haplotypes link to the PARK6 region. We …
mutation analysis in eight inbred families whose haplotypes link to the PARK6 region. We …
Identification of candidate Parkinson disease genes by integrating genome-wide association study, expression, and epigenetic data sets
Importance Substantial genome-wide association study (GWAS) work in Parkinson disease (PD)
has led to the discovery of an increasing number of loci shown reliably to be associated …
has led to the discovery of an increasing number of loci shown reliably to be associated …
Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia
Parkinson’s disease is a genetically complex disorder. Multiple genes have been shown to
contribute to the risk of Parkinson’s disease, and currently 90 independent risk variants have …
contribute to the risk of Parkinson’s disease, and currently 90 independent risk variants have …
Neurological outcome in cerebrotendinous xanthomatosis treated with chenodeoxycholic acid: early versus late diagnosis
…, L Ephraty, H Cohen, S Hassin-Baer - Clinical …, 2013 - journals.lww.com
Objective To present the long-term neurological outcome of Jewish Israeli patients with
cerebrotendinous xanthomatosis (CTX) after several years of chenodeoxycholic acid (CDCA) …
cerebrotendinous xanthomatosis (CTX) after several years of chenodeoxycholic acid (CDCA) …
Higher frequency of certain cancers in LRRK2 G2019S mutation carriers with Parkinson disease: a pooled analysis
Importance Patients with Parkinson disease (PD) who harborLRRK2G2019S mutations may
have increased risks of nonskin cancers. However, the results have been inconsistent …
have increased risks of nonskin cancers. However, the results have been inconsistent …
SMPD1 mutations, activity, and α‐synuclein accumulation in Parkinson's disease
…, KS Marder, UJ Kang, S Hassin‐Baer… - Movement …, 2019 - Wiley Online Library
Background SMPD1 (acid‐sphingomyelinase) variants have been associated with Parkinson's
disease in recent studies. The objective of this study was to further investigate the role of …
disease in recent studies. The objective of this study was to further investigate the role of …
Sequence Variants in SLC6A3, DRD2, and BDNF Genes and Time to Levodopa-Induced Dyskinesias in Parkinson's Disease
…, E Friedman, S Rosset, S Hassin-Baer - Journal of Molecular …, 2014 - Springer
Levodopa-induced dyskinesias (LID) present a common but elusive complication of levodopa
therapy in Parkinson’s disease (PD). In order to identify genetic factors associated with LID…
therapy in Parkinson’s disease (PD). In order to identify genetic factors associated with LID…
Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies
Objective The TMEM175/GAK/DGKQ locus is the 3rd strongest risk locus in genome‐wide
association studies of Parkinson disease (PD). We aimed to identify the specific disease‐…
association studies of Parkinson disease (PD). We aimed to identify the specific disease‐…
A diagnostic ceiling for exome sequencing in cerebellar ataxia and related neurological disorders
Genetic ataxias are associated with mutations in hundreds of genes with high phenotypic
overlap complicating the clinical diagnosis. Whole‐exome sequencing (WES) has increased …
overlap complicating the clinical diagnosis. Whole‐exome sequencing (WES) has increased …