Background: Treatment of moderate or severe chronic obstructive pulmonary disease (COPD)
with combinations of inhaled corticosteroids, long-acting β-agonists, and long-acting …

When is it legitimate to exclude randomised patients from the analysis of data in clinical trials?
Basing their analysis on the desirability of minimising bias and random error, the authors …

There is increasing evidence that chronic obstructive pulmonary disease (COPD) is associated
with chronic inflammation in the airways and lung parenchyma; however, little is known …

… Contributors: Shawn Aaron had full access to all of the data in the study and takes …
Shawn Aaron drafted the manuscript; the other authors revised the manuscript critically for …

Background In this randomized, double-blind, placebo-controlled trial, we studied the
effectiveness of prednisone in reducing the risk of relapse after outpatient exacerbations of chronic …

Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …

Background The relevance of Aspergillus fumigatus in patients with cystic fibrosis (CF) not
affected by allergic bronchopulmonary aspergillosis is unclear. Our aim was to determine the …

Background Population-based studies have documented an association between obesity
and an increased prevalence of asthma in women. Methods We prospectively studied 58 …

Standardized susceptibility testing fails to predict in vivo resistance of device-related infections
to antimicrobials. We assessed agents and combinations of antimicrobials against clinical …

Background Retrospective studies have shown that statins decrease the rate and severity of
exacerbations, the rate of hospitalization, and mortality in chronic obstructive pulmonary …