Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …

Neuroanatomically precise, genome-wide maps of transcript distributions are critical resources
to complement genomic sequence data and to correlate functional and genetic brain …

The anatomical and functional architecture of the human brain is mainly determined by prenatal
transcriptional processes. We describe an anatomically comprehensive atlas of the mid-…

Nervous systems are composed of various cell types, but the extent of cell type diversity is
poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual …

The neocortex contains a multitude of cell types that are segregated into layers and functionally
distinct areas. To investigate the diversity of cell types across the mouse neocortex, here …

Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-…

Transcriptomic profiling of complex tissues by single-nucleus RNA-sequencing (snRNA-seq)
affords some advantages over single-cell RNA-sequencing (scRNA-seq). snRNA-seq …

Understanding the diversity of cell types in the brain has been an enduring challenge and
requires detailed characterization of individual neurons in multiple dimensions. To …

The transcriptional underpinnings of brain development remain poorly understood,
particularly in humans and closely related non-human primates. We describe a high-resolution …

Abundant evidence supports the presence of at least three distinct types of thalamocortical (TC)
neurons in the primate dorsal lateral geniculate nucleus (dLGN) of the thalamus, the …