User profiles for Shefah Qazi
Shefah QaziIndiana University Verified email at indiana.edu Cited by 820 |
Use of the interior cavity of the P22 capsid for site-specific initiation of atom-transfer radical polymerization with high-density cargo loading
Virus-like particles (VLPs) have emerged as important and versatile architectures for
chemical manipulation in the development of functional hybrid nanostructures. Here we …
chemical manipulation in the development of functional hybrid nanostructures. Here we …
Functional virus-based polymer–protein nanoparticles by atom transfer radical polymerization
Viruses and virus-like particles (VLPs) are useful tools in biomedical research. Their defined
structural attributes make them attractive platforms for engineered interactions over large …
structural attributes make them attractive platforms for engineered interactions over large …
Programmed self-assembly of an active P22-Cas9 nanocarrier system
S Qazi, HM Miettinen, RA Wilkinson… - Molecular …, 2016 - ACS Publications
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) RNA-guided
endonucleases are powerful new tools for targeted genome engineering. These nucleases provide …
endonucleases are powerful new tools for targeted genome engineering. These nucleases provide …
P22 viral capsids as nanocomposite high-relaxivity MRI contrast agents
S Qazi, LO Liepold, MJ Abedin, B Johnson… - Molecular …, 2013 - ACS Publications
Attachment of multiple chelated Gd 3+ ions to the interior of bacteriophage P22 viral capsids
affords nanoscale MRI contrast agents with extremely high relaxivity values. Highly …
affords nanoscale MRI contrast agents with extremely high relaxivity values. Highly …
Revisiting an old friend: new findings in alphavirus structure and assembly
Highlights • Both the E2 and E1 glycoproteins interact with the cellular Mxr8 receptor. • TF
virulence factor production correlates with structural polyprotein topology. • Some …
virulence factor production correlates with structural polyprotein topology. • Some …
Manganese(III) porphyrins complexed with P22 virus-like particles as T 1-enhanced contrast agents for magnetic resonance imaging
Virus-like particles are powerful platforms for the development of functional hybrid materials.
Here, we have grown a cross-linked polymer (cross-linked aminoethyl methacrylate) within …
Here, we have grown a cross-linked polymer (cross-linked aminoethyl methacrylate) within …
Gadolinium-loaded viral capsids as magnetic resonance imaging contrast agents
Polymeric nanohybrid P22 virus capsids were used as templates for high density Gd 3+
loading to explore magnetic field-dependent (0.5–7.0 T) proton relaxivity. The field-dependence …
loading to explore magnetic field-dependent (0.5–7.0 T) proton relaxivity. The field-dependence …
An assembly-activating site in the hepatitis B virus capsid protein can also trigger disassembly
S Qazi, CJ Schlicksup, J Rittichier… - ACS chemical …, 2018 - ACS Publications
The Hepatitis B Virus (HBV) core protein homodimers self-assemble to form an icosahedral
capsid that packages the viral genome. Disassembly occurs in the nuclear basket to release …
capsid that packages the viral genome. Disassembly occurs in the nuclear basket to release …
Virion-associated polyamines transmit with bunyaviruses to maintain infectivity and promote entry
V Mastrodomenico, JJ Esin, S Qazi… - ACS Infectious …, 2020 - ACS Publications
Viruses require host cell metabolites to productively infect, and the mechanisms by which
viruses usurp these molecules are diverse. One group of cellular metabolites important in virus …
viruses usurp these molecules are diverse. One group of cellular metabolites important in virus …
Changes in the stability and biomechanics of P22 bacteriophage capsid during maturation
The capsid of P22 bacteriophage undergoes a series of structural transitions during
maturation that guide it from spherical to icosahedral morphology. The transitions include the …
maturation that guide it from spherical to icosahedral morphology. The transitions include the …