Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors,
and has been reproducibly associated with future cardio-metabolic health outcomes. In …

Birth weight within the normal range is associated with a variety of adult-onset diseases, but
the mechanisms behind these associations are poorly understood 1 . Previous genome-…

The causes of impaired skeletal muscle mass and strength during aging are well-studied in
healthy populations. Less is known on pathological age-related muscle wasting and …

Genome-wide association studies of birth weight have focused on fetal genetics, whereas
relatively little is known about the role of maternal genetic variation. We aimed to identify …

Rationale: Asthma is a chronic inflammatory airway disease that affects more than 300
million individuals worldwide. Asthma is caused by interaction of genetic and environmental …

Common genetic variants have been identified for adult height, but not much is known
about the genetics of skeletal growth in early life. To identify common genetic variants that …

Background Higher maternal plasma glucose (PG) concentrations, even below gestational
diabetes mellitus (GDM) thresholds, are associated with adverse offspring outcomes, with …

The FTO gene harbors variation with the strongest effect on adiposity and obesity risk.
Previous data support a role for FTO variation in influencing food intake. We conducted a …

Early childhood growth patterns are associated with adult health, yet the genetic factors and
the developmental stages involved are not fully understood. Here, we combine genome-…

Sarcopenia is associated with adverse health outcomes. This study investigated whether
skeletal muscle gene expression was associated with lean mass and grip strength in …