User profiles for Shekhar Saha

Shekhar Saha

- Verified email at virginia.edu - Cited by 441

Shekhar Saha

- Verified email at med.uni-muenchen.de - Cited by 315

Surgical explantation after TAVR failure: mid-term outcomes from the EXPLANT-TAVR international registry

VN Bapat, S Zaid, S Fukuhara, S Saha… - Cardiovascular …, 2021 - jacc.org
Objectives The aim of this study was to evaluate clinical characteristics, mechanisms of failure,
and outcomes of transcatheter aortic valve replacement (TAVR) explantation. Background …

ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines

P Kumar, S Kiran, S Saha, Z Su, T Paulsen… - Science …, 2020 - science.org
Extrachromosomal circular DNAs (eccDNAs) are somatically mosaic and contribute to
intercellular heterogeneity in normal and tumor cells. Because short eccDNAs are poorly …

[HTML][HTML] PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis

…, B Tran, VL Gordon, C Morris, S Saha… - The Journal of …, 2023 - Am Soc Clin Investig
Targeted therapies such as venetoclax (VEN) (Bcl-2 inhibitor) have revolutionized the treatment
of chronic lymphocytic leukemia (CLL). We previously reported that persister CLL cells …

Sarcopenia as prognostic factor in lung cancer patients: a systematic review and meta-analysis

…, C Roever, H Bohnenberger, S Saha… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Sarcopenia describes the loss of skeletal muscle mass. While this
condition is associated with a high mortality in cancer patients, its influence on survival is still …

[HTML][HTML] Non-communicable disease (NCD) risk factors and diabetes among adults living in slum areas of Dhaka, Bangladesh

LB Rawal, T Biswas, NN Khandker, SR Saha… - PloS one, 2017 - journals.plos.org
Background Despite one-third of the urban population in Bangladesh living in urban slums
and at increased risk of non-communicable diseases (NCDs), little is known about the NCD …

Long noncoding RNA DRAIC inhibits prostate cancer progression by interacting with IKK to inhibit NF-κB activation

S Saha, M Kiran, C Kuscu, A Chatrath, D Wotton… - Cancer research, 2020 - AACR
Shekhar Saha; Shekhar SahaShekhar Saha, Manjari Kiran, Canan Kuscu, Ajay Chatrath,
David Wotton, Marty W. Mayo, Anindya Dutta; Long Noncoding RNA DRAIC Inhibits Prostate …

Explant vs redo-TAVR after transcatheter valve failure: mid-term outcomes from the EXPLANTORREDO-TAVR international registry

…, O De Backer, L Søndergaard, S Saha… - Cardiovascular …, 2023 - jacc.org
Background Valve reintervention after transcatheter aortic valve replacement (TAVR) failure
has not been studied in detail. Objectives The authors sought to determine outcomes of …

The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK

S Saha, Y Zhang, B Wilson… - Journal of Cell …, 2021 - journals.biologists.com
Long noncoding RNAs (lncRNAs) are long RNA transcripts that do not code for proteins and
have been shown to play a major role in cellular processes through diverse mechanisms. …

[PDF][PDF] Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors

RK Przanowska, CA Weidmann, S Saha… - Cell reports, 2022 - cell.com
Many lncRNAs have been discovered using transcriptomic data; however, it is unclear what
fraction of lncRNAs is functional and what structural properties affect their phenotype. MUNC …

[HTML][HTML] The pan-cancer landscape of prognostic germline variants in 10,582 patients

A Chatrath, R Przanowska, S Kiran, Z Su, S Saha… - Genome medicine, 2020 - Springer
Background While clinical factors such as age, grade, stage, and histological subtype provide
physicians with information about patient prognosis, genomic data can further improve …