User profiles for Shemin Lu

Shemin Lu (吕社民)

Professor of Biochemistry and Molecular Biology, Xi'an Jiaotong University School of …
Verified email at mail.xjtu.edu.cn
Cited by 21394

[HTML][HTML] Molecular immune pathogenesis and diagnosis of COVID-19

X Li, M Geng, Y Peng, L Meng, S Lu - Journal of pharmaceutical analysis, 2020 - Elsevier
Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia which is caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The emergence of SARS-CoV-…

Positional identification of Ncf1 as a gene that regulates arthritis severity in rats

P Olofsson, J Holmberg, J Tordsson, S Lu… - Nature …, 2003 - nature.com
The identification of genes underlying quantitative-trait loci (QTL) for complex diseases,
such as rheumatoid arthritis, is a challenging and difficult task for the human genome project. …

Arthritis induced in rats with non‐immunogenic adjuvants as models for rheumatoid arthritis

R Holmdahl, JC Lorentzen, S Lu… - Immunological …, 2001 - Wiley Online Library
Rat models are useful for studies of the pathogenesis of rheumatoid arthritis (RA) since rats
are extraordinarily sensitive to induction of arthritis with adjuvants. Injection of not only the …

[PDF][PDF] A novel long noncoding RNA Lnc‐HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism

…, J Sun, L Meng, W Zhu, R Holmdahl, D Li, S Lu - …, 2016 - Wiley Online Library
Cholesterol metabolism disorder in hepatocytes predicts a higher risk of metabolic syndrome
(MetS). Long noncoding RNAs (lncRNAs) have emerged as critical players in cellular …

[HTML][HTML] Dependence of SARS-CoV-2 infection on cholesterol-rich lipid raft and endosomal acidification

…, L He, L Zhang, R Holmdahl, L Meng, S Lu - Computational and …, 2021 - Elsevier
Coronavirus disease 2019 is a kind of viral pneumonia caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). However, the mechanism whereby SARS-CoV-2 …

Regulation of osteoblast proliferation and differentiation by interrod spacing of Sr-HA nanorods on microporous titania coatings

J Zhou, B Li, S Lu, L Zhang, Y Han - ACS applied materials & …, 2013 - ACS Publications
Strontium-doped hydroxyapatite (Ca 9 Sr 1 (PO 4 ) 6 (OH) 2 , Sr 1 -HA) nanorods with different
lateral spacing (eg, interrod spacing) values (67.3 ± 3.8, 95.7 ± 4.2, and 136.8 ± 8.7 nm) …

[HTML][HTML] Adipose tissue macrophages as potential targets for obesity and metabolic diseases

X Li, Y Ren, K Chang, W Wu, HR Griffiths, S Lu… - Frontiers in …, 2023 - frontiersin.org
Macrophage infiltration into adipose tissue is a key pathological factor inducing adipose tissue
dysfunction and contributing to obesity-induced inflammation and metabolic disorders. In …

[HTML][HTML] MicroRNA-26a negatively regulates toll-like receptor 3 expression of rat macrophages and ameliorates pristane induced arthritis in rats

…, Q Ning, Y Han, H Yu, J Sun, L Meng, S Lu - Arthritis research & …, 2014 - Springer
Introduction Abnormal toll-like receptor (TLR)3 signaling plays an indispensable role in
pathogenesis of both experimental and human rheumatoid arthritis, and microRNAs (miRNAs) …

Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus

…, T Hu, J Lu, X Wang, H Zhou, W Ta, Y Wang, S Lu… - Phytomedicine, 2020 - Elsevier
Background The novel coronavirus disease (2019-nCoV) has been affecting global health
since the end of 2019 and there is no sign that the epidemic is abating . The major issue for …

[HTML][HTML] Animal models of rheumatoid arthritis (I): pristane-induced arthritis in the rat

…, A Fischer, A Leichsenring, F Lange, C Haase, S Lu… - PLoS …, 2016 - journals.plos.org
Background To facilitate the development of therapies for rheumatoid arthritis (RA), the
Innovative Medicines Initiative BTCure has combined the experience from several laboratories …