User profiles for Sheng-Ting Hung

Sheng-Ting Hung

National Sun Yat-sen University
Verified email at mail.nsysu.edu.tw
Cited by 635

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

…, M Chromiński, ZE Holmes, ST Hung… - Nature chemical …, 2018 - nature.com
RNAs directly regulate a vast array of cellular processes, emphasizing the need for robust
approaches to fluorescently label and track RNAs in living cells. Here, we develop an RNA …

Syntheses and quadratic nonlinear optical properties of salts containing benzothiazolium electron-acceptor groups

…, JA Harris, JJ Hall, BS Brunschwig, ST Hung… - Chemistry of …, 2006 - ACS Publications
A series of chromophoric salts has been prepared in which electron-rich 4-(dimethylamino)phenyl
groups are connected via polyenyl chains to electron-accepting N-methylpyridinium or …

Directed evolution of a bright variant of mCherry: suppression of nonradiative decay by fluorescence lifetime selections

S Mukherjee, P Manna, ST Hung… - The Journal of …, 2022 - ACS Publications
The approximately linear scaling of fluorescence quantum yield (ϕ) with fluorescence lifetime
(τ) in fluorescent proteins (FPs) has inspired engineering of brighter fluorophores based on …

The roles of molecular structure and effective optical symmetry in evolving dipolar chromophoric building blocks to potent octopolar nonlinear optical chromophores

T Ishizuka, LE Sinks, K Song, ST Hung… - Journal of the …, 2011 - ACS Publications
A series of mono-, bis-, tris-, and tetrakis(porphinato)zinc(II) (PZn)-elaborated ruthenium(II)
bis(terpyridine) (Ru) complexes have been synthesized in which an ethyne unit connects the …

Engineering of a brighter variant of the fusionred fluorescent protein using lifetime flow cytometry and structure-guided mutations

S Mukherjee, ST Hung, N Douglas, P Manna… - Biochemistry, 2020 - ACS Publications
The development of fluorescent proteins (FPs) has revolutionized biological imaging.
FusionRed, a monomeric red FP (RFP), is known for its low cytotoxicity and correct localization of …

Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter

P Manna, ST Hung, S Mukherjee, P Friis… - Integrative …, 2018 - academic.oup.com
Green fluorescent proteins (GFP) and their blue, cyan and red counterparts offer
unprecedented advantages as biological markers owing to their genetic encodability and …

[PDF][PDF] Molecular Symmetry and Solution‐Phase Structure Interrogated by Hyper‐Rayleigh Depolarization Measurements: Elaborating Highly Hyperpolarizable D2 …

TV Duncan, K Song, ST Hung, I Miloradovic… - Angewandte …, 2008 - academia.edu
It has long been recognized that the measured magnitudes of dynamic hyperpolarizabilities
(bl values) can depend sensitively on molecular structure.[1] Whether a chromophore with …

Enrichment of rare events using a multi-parameter high throughput microfluidic droplet sorter

ST Hung, S Mukherjee, R Jimenez - Lab on a Chip, 2020 - pubs.rsc.org
High information content analysis, enrichment, and selection of rare events from a large
population are of great importance in biological and biomedical research. The fluorescence …

Microfluidic organic bioelectronic chips for efficient isolation of trophoblast cells using a combination of rational catenation and electrically controllable refining

…, SC Yen, PI Wu, ED Quinones, ST Hung… - Materials Chemistry and …, 2022 - Elsevier
The non-invasive prenatal test (NIPT) has become the global standard for effective prenatal
screening for newborn health care. Recently, there has been rapid growth in next-generation …

Characterizing dark state kinetics and single molecule fluorescence of FusionRed and FusionRed-MQ at low irradiances

…, R Wilson, E Simmerman, ST Hung… - Physical Chemistry …, 2022 - pubs.rsc.org
The presence of dark states causes fluorescence intermittency of single molecules due to
transitions between “on” and “off” states. Genetically encodable markers such as fluorescent …