Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system

…, J Ye, J Yang, L Zhao, DM Altmann, S Cao… - Nature …, 2022 - nature.com
Recent studies have demonstrated that brain meningeal lymphatic vessels (MLVs) act as a
drainage path directly into the cervical lymph nodes (CLNs) for macromolecules contained in …

Viral infection of the central nervous system and neuroinflammation precede blood-brain barrier disruption during Japanese encephalitis virus infection

F Li, Y Wang, L Yu, S Cao, K Wang, J Yuan… - Journal of …, 2015 - Am Soc Microbiol
Japanese encephalitis is an acute zoonotic, mosquito-borne disease caused by Japanese
encephalitis virus (JEV). Japanese encephalitis is characterized by extensive inflammation in …

[HTML][HTML] Usutu virus: an emerging flavivirus in Europe

U Ashraf, J Ye, X Ruan, S Wan, B Zhu, S Cao - Viruses, 2015 - mdpi.com
Usutu virus (USUV) is an African mosquito-borne flavivirus belonging to the Japanese
encephalitis virus serocomplex. USUV is closely related to Murray Valley encephalitis virus, …

Immune evasion strategies of flaviviruses

J Ye, B Zhu, ZF Fu, H Chen, S Cao - Vaccine, 2013 - Elsevier
Flavivirus is a genus of the family Flaviviridae. It includes West Nile virus (WNV), dengue
virus (DENV), yellow fever virus (YFV), Japanese encephalitis virus (JEV), tick-borne …

Benzoxazine monomer derived carbon dots as a broad-spectrum agent to block viral infectivity

…, L Shao, Y Song, X Zheng, F Cao, S Cao - Journal of colloid and …, 2019 - Elsevier
Multiple viruses can cause infection and death of millions annually. Of these, flaviviruses are
found to be highly prevalent in recent years with no distinctive antiviral therapies. Therefore, …

Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage

U Ashraf, Z Ding, S Deng, J Ye, S Cao, Z Chen - Virulence, 2021 - Taylor & Francis
Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by
Japanese encephalitis virus. During the virus infection of the central nervous system, reactive …

[HTML][HTML] Roles of TLR3 and RIG-I in mediating the inflammatory response in mouse microglia following Japanese encephalitis virus infection

…, J Ye, B Zhu, Y Song, H Chen, S Cao - Journal of immunology …, 2014 - hindawi.com
Japanese encephalitis virus (JEV) infection can cause central nervous system disease with
irreversible neurological damage in humans and animals. Evidence suggests that …

MicroRNA-15b modulates Japanese encephalitis virus–mediated inflammation via targeting RNF125

…, X Duan, ZF Fu, Y Song, H Chen, S Cao - The Journal of …, 2015 - journals.aai.org
Japanese encephalitis virus (JEV) can target CNS and cause neuroinflammation that is
characterized by profound neuronal damage and concomitant microgliosis/astrogliosis. Although …

Japanese encephalitis virus NS5 inhibits type I interferon (IFN) production by blocking the nuclear translocation of IFN regulatory factor 3 and NF-κB

…, Y Song, C Deng, B Zhang, H Chen, S Cao - Journal of …, 2017 - Am Soc Microbiol
The type I interferon (IFN) response is part of the first-line defense against viral infection. To
initiate replication, viruses have developed powerful evasion strategies to counteract host …

MicroRNA-19b-3p modulates Japanese encephalitis virus-mediated inflammation via targeting RNF11

…, C Wang, X Duan, H Zhang, H Chen, S Cao - Journal of …, 2016 - Am Soc Microbiol
Japanese encephalitis virus (JEV) can invade the central nervous system and consequently
induce neuroinflammation, which is characterized by profound neuronal cell damage …