User profiles for Shengce Tao

Sheng-ce Tao

Professor of Systems Biology, Shanghai Jiao Tong University
Verified email at sjtu.edu.cn
Cited by 6371

Advances and utility of the human plasma proteome

…, Y Vandenbrouck, V Brun, S Tao… - Journal of proteome …, 2021 - ACS Publications
The study of proteins circulating in blood offers tremendous opportunities to diagnose, stratify,
or possibly prevent diseases. With recent technological advances and the urgent need to …

[HTML][HTML] Nucleic acid testing of SARS-CoV-2: A review of current methods, challenges, and prospects

Y Zhu, M Zhang, Z Jie, S Tao - Frontiers in Microbiology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and has brought a huge threat to public health and the global …

Protein microarrays for systems biology

L Yang, S Guo, Y Li, S Zhou, S Tao - Acta Biochim Biophys Sin, 2011 - academic.oup.com
Abstract Systems biology holds the key for understanding biological systems on a system
level. It eventually holds the key for the treatment and cure of complex diseases such as cancer…

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

…, M Gao, S Chang, YC Xie, G Tian, HW Jiang, SC Tao… - Science, 2020 - science.org
The pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has become a global crisis. Replication of SARS-…

Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells

Y Liao, J Ling, G Zhang, F Liu, S Tao, Z Han, S Chen… - Cell cycle, 2015 - Taylor & Francis
Cordycepin, an adenosine analog derived from Cordyceps militaris has been shown to
exert anti-tumor activity in many ways. However, the mechanisms by which cordycepin …

[HTML][HTML] SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70

…, H Qi, J Zhang, PH Wang, ZG Han, S Tao - Cellular & molecular …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2. 1 As of July 16th, 2020, there were 13,579,581
diagnosed cases and 584,782 deaths attributed to COVID-19 reported globally (https://coronavirus…

[HTML][HTML] SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

…, X Yang, H Qi, H Li, D Men, J Zhou, S Tao - Nature …, 2020 - nature.com
We still know very little about how the human immune system responds to SARS-CoV-2.
Here we construct a SARS-CoV-2 proteome microarray containing 18 out of the 28 predicted …

Microfluidic chip integrating high throughput continuous-flow PCR and DNA hybridization for bacteria analysis

X Jiang, N Shao, W Jing, S Tao, S Liu, G Sui - Talanta, 2014 - Elsevier
Rapid identification of clinical pathogens is the initial and essential step for antimicrobial
therapy. Herein, we successfully developed a microfluidic device which combines high-…

[HTML][HTML] Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis

Y Lin, J Lu, J Zhang, W Walter, W Dang, J Wan, SC Tao… - Cell, 2009 - cell.com
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) conduct many critical
functions through nonhistone substrates in metazoans, but only chromatin-associated …

A graphene oxide coated tapered microfiber acting as a super-sensor for rapid detection of SARS-CoV-2

H Jia, A Zhang, Y Yang, Y Cui, J Xu, H Jiang, S Tao… - Lab on a Chip, 2021 - pubs.rsc.org
COVID-19 is a new strain of highly contagious coronavirus, and at present, more than 221.4
million people have been infected with this virus, and the death toll exceeds 2793398. Early …