Classical genetic screens can be limited by the selectivity of mutational targeting, the
complexities of anatomically based phenotypic analysis, or difficulties in subsequent gene …

The dispatched (disp) gene is required for long-range Hedgehog (Hh) signaling in
Drosophila. Here, we demonstrate that one of two murine homologs, mDispA, can rescue disp …

The ihog gene (interference hedgehog), identified by RNA interference in Drosophila cultured
cells, encodes a type 1 membrane protein shown here to bind and to mediate response to …

In humans and other mammalian species, lesions in the preoptic area of the hypothalamus
cause profound sleep impairment 1 , 2 , 3 , 4 , 5 , indicating a crucial role of the preoptic area …

An essential step toward understanding brain function is to establish a structural framework
with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and …

Parental care is essential for the survival of mammals, yet the mechanisms underlying its
evolution remain largely unknown. Here we show that two sister species of mice, Peromyscus …

Recombinant rabies viral vectors have proven useful for applications including retrograde
targeting of projection neurons and monosynaptic tracing, but their cytotoxicity has limited their …

Rapid cell type identification by new genomic single-cell analysis methods has not been met
with efficient experimental access to these cell types. To facilitate access to specific neural …

Sleep disturbances are strongly associated with cardiovascular diseases. Baroreflex, a basic
cardiovascular regulation mechanism, is modulated by sleep-wake states. Here, we show …

10.7554/eLife.31373.001 The neural control of social behaviors in rodents requires the
encoding of pheromonal cues by the vomeronasal system. Here we show that the typical …