[PDF][PDF] The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response
…, MT Kinter, PM Rindler, S Zacchigna, S Mukherjee… - Cell, 2014 - cell.com
The mammalian heart has a remarkable regenerative capacity for a short period of time after
birth, after which the majority of cardiomyocytes permanently exit cell cycle. We sought to …
birth, after which the majority of cardiomyocytes permanently exit cell cycle. We sought to …
Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior
S Mukherjee, L Coque, JL Cao, J Kumar… - Biological …, 2010 - Elsevier
BACKGROUND: Circadian rhythm abnormalities are strongly associated with bipolar
disorder; however the role of circadian genes in mood regulation is unclear. Previously, we …
disorder; however the role of circadian genes in mood regulation is unclear. Previously, we …
Hedgehog signaling and response to cyclopamine differs in epithelial and stromal cells in benign breast and breast cancer
S Mukherjee, N Frolova, A Sadlonova… - Cancer biology & …, 2006 - Taylor & Francis
The hedgehog pathway regulates epithelial-mesenchymal interactions, differentiation,
proliferation and survival during development. Stimulation of hedgehog signaling induces …
proliferation and survival during development. Stimulation of hedgehog signaling induces …
RAD51 interconnects between DNA replication, DNA repair and immunity
…, EK Wakeland, S Ghose, S Mukherjee… - Nucleic acids …, 2017 - academic.oup.com
RAD51, a multifunctional protein, plays a central role in DNA replication and homologous
recombination repair, and is known to be involved in cancer development. We identified a …
recombination repair, and is known to be involved in cancer development. We identified a …
Role of nuclear factor κB in ovarian hormone-mediated stress hypersensitivity in female mice
Q LaPlant, S Chakravarty, V Vialou, S Mukherjee… - Biological …, 2009 - Elsevier
BACKGROUND: The molecular mechanisms of stress-induced depressive behaviors have
been characterized extensively in male rodents; however, much less is known about female …
been characterized extensively in male rodents; however, much less is known about female …
Human ventricular unloading induces cardiomyocyte proliferation
DC Canseco, W Kimura, S Garg, S Mukherjee… - Journal of the American …, 2015 - jacc.org
Background : The adult mammalian heart is incapable of meaningful regeneration after
substantial cardiomyocyte loss, primarily due to the inability of adult cardiomyocytes to divide. …
substantial cardiomyocyte loss, primarily due to the inability of adult cardiomyocytes to divide. …
Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety‐related behavior
…, J Kumar, V Krishnan, S Mukherjee… - European Journal of …, 2013 - Wiley Online Library
It has been suggested for some time that circadian rhythm abnormalities underlie the
development of multiple psychiatric disorders. However, it is unclear how disruptions in individual …
development of multiple psychiatric disorders. However, it is unclear how disruptions in individual …
[HTML][HTML] Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 …
Lithium has been used extensively for mood stabilization, and it is particularly efficacious in
the treatment of bipolar mania. Like other drugs used in the treatment of psychiatric diseases, …
the treatment of bipolar mania. Like other drugs used in the treatment of psychiatric diseases, …
Separation of telomerase functions by reverse genetics
S Mukherjee, EJ Firpo, Y Wang… - Proceedings of the …, 2011 - National Acad Sciences
The canonical function of the human telomerase protein (hTERT) is to synthesize telomeric
DNA, but it has other biological activities, including enhancing cell proliferation, decreasing …
DNA, but it has other biological activities, including enhancing cell proliferation, decreasing …
[HTML][HTML] c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells
S Mukherjee, SE Conrad - Journal of biological chemistry, 2005 - ASBMB
Estrogen rapidly induces expression of the proto-oncogene c-myc. c-Myc is required for
estrogen-stimulated proliferation of breast cancer cells, and deregulated c-Myc expression has …
estrogen-stimulated proliferation of breast cancer cells, and deregulated c-Myc expression has …