Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells

T Kawahara, Y Kuwano, S Teshima-Kondo… - The Journal of …, 2004 - journals.aai.org
The NADPH oxidase 1 (Nox1) is a gp91 phox homologue preferentially expressed in the colon.
We have established primary cultures of guinea pig large intestinal epithelial cells giving …

Helicobacter pylori lipopolysaccharide activates Rac1 and transcription of NADPH oxidase Nox1 and its organizer NOXO1 in guinea pig gastric mucosal cells

…, H Mino, S Teshima-Kondo… - … of Physiology-Cell …, 2005 - journals.physiology.org
Primary cultures of guinea pig gastric mucosal cells express NADPH oxidase 1 (Nox1), a
homolog of gp91 phox , and produce superoxide anion (O 2 − ) at a rate of ∼100 nmol·mg …

Interferon-γ activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells

…, H Yamamoto, S Teshima-Kondo… - … of Physiology-Cell …, 2006 - journals.physiology.org
NADPH oxidase 1 (Nox1), a homolog of gp91 phox , is dominantly expressed in large
intestinal epithelium, and reactive oxygen species derived from Nox1 are suggested to serve a …

NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis

…, A Sekiyama, S Teshima-Kondo - Antioxidants & redox …, 2006 - liebertpub.com
The gastrointestinal epithelium functions as physical and innate immune barriers against
commensal or pathogenic microbes. NADPH oxidase 1 (Nox1) and dual oxidase 2 (Duox2), …

Nox enzymes and oxidative stress in the immunopathology of the gastrointestinal tract

…, K Tominaga, K Nishida, S Teshima-Kondo - Seminars in …, 2008 - Springer
Chronic inflammation caused by Helicobacter pylori infection or inflammatory bowel disease
(IBD) is closely linked to cancer development. Innate immune abnormalities and enhanced …

NADPH oxidase-derived reactive oxygen species are essential for differentiation of a mouse macrophage cell line (RAW264. 7) into osteoclasts

…, K Masuda, T Kawai, S Teshima-Kondo… - The Journal of Medical …, 2009 - jstage.jst.go.jp
Reactive oxygen species (ROS) derived from NADPH oxidase (Nox) homologues have
been suggested to regulate osteoclast differentiation. However, no bone abnormalities have …

Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells

…, EM Mills, S Teshima-Kondo… - … of Physiology-Cell …, 2018 - journals.physiology.org
Unloading-mediated muscle atrophy is associated with increased reactive oxygen species (ROS)
production. We previously demonstrated that elevated ubiquitin ligase casitas B-…

Evidence for cancer-associated expression of NADPH oxidase 1 (Nox1)-based oxidase system in the human stomach

…, H Sasaki, T Kawai, S Teshima-Kondo… - Free Radical Biology …, 2007 - Elsevier
Helicobacter pylori infection has been suggested to stimulate expression of the NADPH
oxidase 1 (Nox1)-based oxidase system in guinea pig gastric epithelium, whereas Nox1 mRNA …

Tumor necrosis factor α activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells

…, K Masuda, T Kawai, S Teshima-Kondo… - Free Radical Biology …, 2008 - Elsevier
NADPH oxidase 1 (Nox1) is a multicomponent enzyme consisting of p22 phox , Nox organizer
1 (NOXO1), Nox1 activator 1, and Rac1. Interleukin-1β, flagellin, interferon-γ, and tumor …

Interleukin 10 inhibits interferon γ-and tumor necrosis factor α-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon

…, Y Yamamoto, T Kawai, S Teshima-Kondo… - Journal of …, 2009 - Springer
Background NADPH oxidase 1 (Nox1) is preferentially expressed in the colon, but its functional
role is not fully understood. This study was designed to elucidate a potential role of Nox1 …