User profiles for Shih-Jen Tsai

Shih-Jen Tsai, 蔡世仁

Professor, Department of Psychiatry, Taipei Veterans General Hospital
Verified email at vghtpe.gov.tw
Cited by 24123

The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression

JP Hwang, SJ Tsai, CJ Hong, CH Yang, JF Lirng… - Neurobiology of …, 2006 - Elsevier
Brain-derived neurotrophic-factor (BDNF), the most abundant of the neurotrophins in the
brain, has been implicated in both major depression and cognitive function. This study …

Association study of a brain‐derived neurotrophic‐factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response

SJ Tsai, CY Cheng, YWY Yu, TJ Chen… - American Journal of …, 2003 - Wiley Online Library
Preclinical studies have shown that brain‐derived neurotrophic factor (BDNF) may be involved
in both antidepressant action and the pathophysiology of major depressive disorder (MDD…

[HTML][HTML] New targets for schizophrenia treatment beyond the dopamine hypothesis

AC Yang, SJ Tsai - International journal of molecular sciences, 2017 - mdpi.com
Schizophrenia has been primarily associated with dopamine dysfunction, and treatments
have been developed that target the dopamine pathway in the central nervous system. …

Inflammatory bowel disease is associated with higher dementia risk: a nationwide longitudinal study

B Zhang, HE Wang, YM Bai, SJ Tsai, TP Su, TJ Chen… - Gut, 2021 - gut.bmj.com
Objective Increasing evidence supports reciprocal communication between the enteric and
the central nervous system in disease, termed the ‘gut–brain axis’. Recent findings suggest a …

[HTML][HTML] Role of interleukin-6 in depressive disorder

EYC Ting, AC Yang, SJ Tsai - International journal of molecular sciences, 2020 - mdpi.com
Major depressive disorder (MDD), which is a leading psychiatric illness across the world,
severely affects quality of life and causes an increased incidence of suicide. Evidence from …

Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior

…, SJ Huo, FC Yen, CL Tung, GM Pan, SJ Tsai - …, 2003 - karger.com
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin growth factor family,
has been implicated in both mood disorders and suicidal behavior. This study has …

[HTML][HTML] Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response

YWY Yu, SJ Tsai, CJ Hong, TJ Chen… - …, 2005 - nature.com
Monoamine oxidase A (MAOA), a mitochondrial enzyme involved in the degradation of biogenic
amines, may be implicated in the pathogenesis of major depressive disorder (MDD) and …

Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression

…, XF Wang, J Zhang, W Lin, L Zheng, JC Pu, SJ Tsai… - Brain, 2016 - academic.oup.com
The first brain-wide voxel-level resting state functional connectivity neuroimaging analysis
of depression is reported, with 421 patients with major depressive disorder and 488 control …

Complexity of spontaneous BOLD activity in default mode network is correlated with cognitive function in normal male elderly: a multiscale entropy analysis

…, JF Chen, NE Huang, CK Peng, CP Lin, SJ Tsai - Neurobiology of …, 2013 - Elsevier
The nonlinear properties of spontaneous fluctuations in blood oxygen level-dependent (BOLD)
signals remain unexplored. We test the hypothesis that complexity of BOLD activity is …

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders–Version …

…, D Rujescu, V Starcevic, DJ Stein, SJ Tsai… - The World Journal of …, 2023 - Taylor & Francis
Full article: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for
treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. …