User profiles for Shilei Ding

Shilei Ding

ETH Zurich
Verified email at mat.ethz.ch
Cited by 802

[HTML][HTML] IFITM proteins restrict viral membrane hemifusion

…, YM Zheng, O Golfetto, B Bungart, M Li, S Ding… - PLoS …, 2013 - journals.plos.org
The interferon-inducible transmembrane (IFITM) protein family represents a new class of
cellular restriction factors that block early stages of viral replication; the underlying mechanism …

[PDF][PDF] Cross-sectional evaluation of humoral responses against SARS-CoV-2 spike

…, SP Anand, G Goyette, M Benlarbi, S Ding… - Cell Reports …, 2020 - cell.com
SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting
millions of people and causing hundreds of thousands of deaths. The Spike glycoproteins …

[HTML][HTML] A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques

…, E Narayanan, Q Liu, Y Tsybovsky, K Boswell, S Ding… - Nature medicine, 2021 - nature.com
The development of a protective vaccine remains a top priority for the control of the HIV/AIDS
pandemic. Here, we show that a messenger RNA (mRNA) vaccine co-expressing …

Interfacial Dzyaloshinskii-Moriya interaction and chiral magnetic textures in a ferrimagnetic insulator

S Ding, A Ross, R Lebrun, S Becker, K Lee, I Boventer… - Physical Review B, 2019 - APS
The interfacial Dzyaloshinskii-Moriya interaction (DMI) in multilayers of heavy metal and
ferromagnetic metals enables the stabilization of novel chiral spin structures such as skyrmions. …

Impact of HIV-1 envelope conformation on ADCC responses

J Richard, J Prévost, N Alsahafi, S Ding, A Finzi - Trends in microbiology, 2018 - cell.com
HIV-1 envelope glycoproteins (Env) represent the only virus-specific antigen exposed at the
surface of infected cells. In its unliganded form, Env from primary viruses samples a ‘closed' …

[PDF][PDF] The interferon-inducible MxB protein inhibits HIV-1 infection

Z Liu, Q Pan, S Ding, J Qian, F Xu, J Zhou, S Cen… - Cell host & …, 2013 - cell.com
The interferon-inducible myxovirus resistance (Mx) proteins play important roles in combating
a wide range of virus infections. MxA inhibits many RNA and DNA viruses, whereas the …

[PDF][PDF] Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy

…, K Symmes, M Benlarbi, S Ding… - Immunity, 2021 - cell.com
Neutralizing antibodies (NAbs) are effective in treating COVID-19, but the mechanism of
immune protection is not fully understood. Here, we applied live bioluminescence imaging (BLI) …

[PDF][PDF] A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection

…, I Ullah, J Prévost, WD Tolbert, K Symmes, S Ding… - Cell reports, 2022 - cell.com
Emerging evidence indicates that both neutralizing and Fc-mediated effector functions of
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …

[PDF][PDF] Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

…, DS Terry, J Gorman, W Shi, B Zhang, T Zhou, S Ding… - Cell host & …, 2020 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) mediates viral
entry into cells and is critical for vaccine development against coronavirus disease 2019 (…

[PDF][PDF] Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

…, D Vézina, SP Anand, G Goyette, D Chaterjee, S Ding… - Cell reports, 2022 - cell.com
Emerging variants of concern for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
can transmit more efficiently and partially evade protective immune responses, …