User profiles for Shintaro Kinugawa
Shintaro KinugawaKyushu University Verified email at cardiol.med.kyushu-u.ac.jp Cited by 13375 |
Oxidative stress and heart failure
H Tsutsui, S Kinugawa… - American journal of …, 2011 - journals.physiology.org
Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative
to antioxidant defense, has been shown to play an important role in the pathophysiology of …
to antioxidant defense, has been shown to play an important role in the pathophysiology of …
Mitochondrial oxidative stress and dysfunction in myocardial remodelling
H Tsutsui, S Kinugawa… - Cardiovascular research, 2009 - academic.oup.com
Recent experimental and clinical studies have suggested that oxidative stress is enhanced
in myocardial remodelling and failure. The production of oxygen radicals is increased in the …
in myocardial remodelling and failure. The production of oxygen radicals is increased in the …
JCS/JHFS 2021 guideline focused update on diagnosis and treatment of acute and chronic heart failure
…, T Ide, H Ito, Y Kihara, K Kinugawa, S Kinugawa… - Circulation …, 2021 - jstage.jst.go.jp
After the publication of the revised edition, therapeutic drugs described in “Future Treatment”
were approved and important evidence for pharmacologic therapy and nonpharmacologic …
were approved and important evidence for pharmacologic therapy and nonpharmacologic …
Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium
T Ide, H Tsutsui, S Kinugawa, H Utsumi… - Circulation …, 1999 - Am Heart Assoc
Oxidative stress in the myocardium may play an important role in the pathogenesis of
congestive heart failure (HF). However, the cellular sources and mechanisms for the enhanced …
congestive heart failure (HF). However, the cellular sources and mechanisms for the enhanced …
JCS 2017/JHFS 2017 guideline on diagnosis and treatment of acute and chronic heart failure―digest version―
…, K Okumura, M Ono, M Kitakaze, K Kinugawa… - Circulation …, 2019 - jstage.jst.go.jp
Heart Failure Society (JHFS). The working committee for this project includes members and
collaborators involved in the previous versions of the heart failure guidelines and members …
collaborators involved in the previous versions of the heart failure guidelines and members …
Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium
T Ide, H Tsutsui, S Kinugawa, N Suematsu… - Circulation …, 2000 - Am Heart Assoc
Experimental and clinical studies have suggested an increased production of reactive
oxygen species (ROS) in the failing myocardium. The present study aimed to obtain direct …
oxygen species (ROS) in the failing myocardium. The present study aimed to obtain direct …
Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction
…, H Tsutsui, T Shiomi, N Suematsu, S Kinugawa… - Circulation, 2002 - Am Heart Assoc
Background— Short-term administration of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitors, statins, has been shown to attenuate ischemia-reperfusion injury. …
reductase inhibitors, statins, has been shown to attenuate ischemia-reperfusion injury. …
Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction
…, M Omokawa, S Kinugawa… - Journal of Applied …, 2009 - journals.physiology.org
Although recent studies have reported that low-intensity resistance training with blood flow
restriction could stress the muscle effectively and provide rapid muscle hypertrophy and …
restriction could stress the muscle effectively and provide rapid muscle hypertrophy and …
Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress
S Kinugawa, H Tsutsui, S Hayashidani, T Ide… - Circulation …, 2000 - Am Heart Assoc
Oxidative stress might play an important role in the progression of left ventricular (LV) remodeling
and failure that occur after myocardial infarction (MI). We determined whether reactive …
and failure that occur after myocardial infarction (MI). We determined whether reactive …
Characteristics and outcomes of hospitalized patients with heart failure and reduced vs preserved ejection fraction A report from the Japanese Cardiac Registry of …
…, S Hamaguchi, S Kinugawa… - Circulation …, 2009 - jstage.jst.go.jp
Background: Heart failure (HF) with preserved ejection fraction (EF) is common. We compared
the characteristics, treatments, and outcomes in HF patients with reduced vs preserved EF …
the characteristics, treatments, and outcomes in HF patients with reduced vs preserved EF …