User profiles for Shirlee Wohl

Shirlee Wohl

Brigham and Women's Hospital | Harvard Medical School
Verified email at bwh.harvard.edu
Cited by 4208

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

…, S Jalloh, M Momoh, M Fullah, G Dudas, S Wohl… - science, 2014 - science.org
In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone,
and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to …

[HTML][HTML] Wastewater sequencing reveals early cryptic SARS-CoV-2 variant transmission

…, R Robles-Sikisaka, MA Schwab, E Spencer, S Wohl… - Nature, 2022 - nature.com
As SARS-CoV-2 continues to spread and evolve, detecting emerging variants early is critical
for public health interventions. Inferring lineage prevalence by clinical testing is infeasible …

Virus genomes reveal factors that spread and sustained the Ebola epidemic

…, K West, S Whitmer, MR Wiley, SM Winnicki, S Wohl… - Nature, 2017 - nature.com
The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …

Zika virus evolution and spread in the Americas

HC Metsky, CB Matranga, S Wohl, SF Schaffner… - Nature, 2017 - nature.com
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …

Genomic epidemiology reveals multiple introductions of Zika virus into the United States

…, C Tomkins-Tinch, KL West, SM Winnicki, S Wohl… - Nature, 2017 - nature.com
Zika virus (ZIKV) is causing an unprecedented epidemic linked to severe congenital abnormalities
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …

[HTML][HTML] Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone

DJ Park, G Dudas, S Wohl, A Goba, SLM Whitmer… - Cell, 2015 - cell.com
The 2013–2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …

[HTML][HTML] Genomic analysis of Lassa virus during an increase in cases in Nigeria in 2018

…, SM Winnicki, RR Shah, J Qu, S Wohl… - … England Journal of …, 2018 - Mass Medical Soc
During 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern
among national and international public health agencies. We analyzed 220 Lassa virus …

[PDF][PDF] Repeat COVID-19 molecular testing: correlation of SARS-CoV-2 culture with molecular assays and cycle thresholds

V Gniazdowski, CP Morris, S Wohl, T Mehoke… - Clin Infect Dis, 2020 - academia.edu
Accepted Manuscript Page 1 Accepted Manuscript © The Author(s) 2020. Published by Oxford
University Press for the Infectious Diseases Society of America. This is an Open Access article …

Repeated coronavirus disease 2019 molecular testing: correlation of severe acute respiratory syndrome coronavirus 2 culture with molecular assays and cycle …

V Gniazdowski, C Paul Morris, S Wohl… - Clinical infectious …, 2021 - academic.oup.com
Background Repeated coronavirus disease 2019 (COVID-19) molecular testing can lead to
positive test results after negative results and to multiple positive results over time. The …

[HTML][HTML] Capturing sequence diversity in metagenomes with comprehensive and scalable probe design

…, P Brehio, A Goldfarb, A Piantadosi, S Wohl… - Nature …, 2019 - nature.com
Metagenomic sequencing has the potential to transform microbial detection and
characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a …