Molecular portraits of human breast tumours
…, Ų Fluge, A Pergamenschikov, C Williams, SX Zhu… - nature, 2000 - nature.com
Human breast tumours are diverse in their natural history and in their responsiveness to
treatments 1 . Variation in transcriptional programs accounts for much of the biological diversity …
treatments 1 . Variation in transcriptional programs accounts for much of the biological diversity …
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
…, CF Williams, SX Zhu… - Proceedings of the …, 1999 - National Acad Sciences
cDNA microarrays and a clustering algorithm were used to identify patterns of gene
expression in human mammary epithelial cells growing in culture and in primary human breast …
expression in human mammary epithelial cells growing in culture and in primary human breast …
[HTML][HTML] Transcriptional profiling of long non-coding RNAs and novel transcribed regions across a diverse panel of archived human cancers
…, SX Zhu, R Li, K Montgomery, S Varma, T Gilks, X Guo… - Genome biology, 2012 - Springer
Background Molecular characterization of tumors has been critical for identifying important
genes in cancer biology and for improving tumor classification and diagnosis. Long non-…
genes in cancer biology and for improving tumor classification and diagnosis. Long non-…
Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray
…, K Montgomery, V Mason, SX Zhu… - The American journal …, 2007 - journals.lww.com
The morphologic distinction between prostate and urothelial carcinoma can be difficult. To
identify novel diagnostic markers that may aid in the differential diagnosis of prostate versus …
identify novel diagnostic markers that may aid in the differential diagnosis of prostate versus …
Clinically relevant molecular subtypes in leiomyosarcoma
Purpose: Leiomyosarcoma is a malignant neoplasm with smooth muscle differentiation.
Little is known about its molecular heterogeneity and no targeted therapy currently exists for …
Little is known about its molecular heterogeneity and no targeted therapy currently exists for …
Gene expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ
RNA sequencing (RNA-seq) is a sensitive and accurate method for quantifying gene
expression. Small samples or those whose RNA is degraded, such as formalin-fixed paraffin-…
expression. Small samples or those whose RNA is degraded, such as formalin-fixed paraffin-…
Genome evolution during progression to breast cancer
…, RT Sweeney, AL Brunner, SX Zhu, X Guo… - Genome …, 2013 - genome.cshlp.org
Cancer evolution involves cycles of genomic damage, epigenetic deregulation, and
increased cellular proliferation that eventually culminate in the carcinoma phenotype. Early …
increased cellular proliferation that eventually culminate in the carcinoma phenotype. Early …
[HTML][HTML] MicroRNA profiling of BRCA1/2 mutation-carrying and non-mutation-carrying high-grade serous carcinomas of ovary
…, S Subramanian, AH Beck, I Espinosa, J Senz, SX Zhu… - PloS one, 2009 - journals.plos.org
Background MicroRNAs (miRNA) are 20∼25 nucleotide non-coding RNAs that inhibit the
translation of targeted mRNA, and they have been implicated in the development of human …
translation of targeted mRNA, and they have been implicated in the development of human …
[HTML][HTML] Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the bone
…, I Espinosa, KC Jensen, S Subramanian, SX Zhu… - Modern Pathology, 2008 - Elsevier
Giant cell tumor of the bone (GCTOB) is a primary bone tumor that occurs mainly in young
adults and is capable of locally aggressive growth. Its histologic appearance can resemble a …
adults and is capable of locally aggressive growth. Its histologic appearance can resemble a …
The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-κB signaling
Nasopharyngeal cancer (NPC) is an Epstein-Barr virus (EBV)–positive epithelial malignancy
with an extensive inflammatory infiltrate. Traditional RNA-sequencing techniques …
with an extensive inflammatory infiltrate. Traditional RNA-sequencing techniques …