Gemcitabine plus cisplatin versus fluorouracil plus cisplatin in recurrent or metastatic nasopharyngeal carcinoma: a multicentre, randomised, open-label, phase 3 trial

…, Y Huang, S Hong, Y Yang, G Yu, J Jia, P Peng, X Wu… - The Lancet, 2016 - thelancet.com
Background Outcomes are poor for patients with recurrent or metastatic nasopharyngeal
carcinoma and no well established first-line chemotherapy is available for the disease. We …

[HTML][HTML] Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug …

…, M Loda, LF Westblade, M Cushing, S Wu… - Nature …, 2021 - nature.com
In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
killed over a million people, including >25,000 in New York City (NYC) alone. The …

The therapeutic landscape for cells engineered with chimeric antigen receptors

…, L Liu, GJ Roboz, ML Guzman, AM Melnick, S Wu… - Nature …, 2020 - nature.com
Despite the global rapid increase in the number of clinical trials employing chimeric antigen
receptors (CARs), no comprehensive survey of their scope, targets and design exists. In this …

The role of replanning in fractionated intensity modulated radiotherapy for nasopharyngeal carcinoma

L Zhao, Q Wan, Y Zhou, X Deng, C Xie, S Wu - Radiotherapy and Oncology, 2011 - Elsevier
BACKGROUND AND PURPOSE: Anatomic changing frequently occurred during fractionated
radiotherapy. The aims of this study were to model the potential benefit of adaptive IMRT …

Single-cell sequencing for precise cancer research: progress and prospects

…, SL Marjani, Z Hu, SM Weissman, X Pan, S Wu - Cancer Research, 2016 - AACR
Advances in genomic technology have enabled the faithful detection and measurement of
mutations and the gene expression profile of cancer cells at the single-cell level. Recently, …

[HTML][HTML] Gemcitabine plus cisplatin versus fluorouracil plus cisplatin as first-line therapy for recurrent or metastatic nasopharyngeal carcinoma: final overall survival …

…, G Yu, P Peng, J Peng, J Jia, X Wu… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
METHODS From February 2012 to October 2015, 362 patients were randomly assigned to
receive either GP (gemcitabine 1 g/m 2 once daily on days 1 and 8 and cisplatin 80 mg/m 2 …

Cancer-associated Fibroblast–promoted LncRNA DNM3OS Confers Radioresistance by Regulating DNA Damage Response in Esophageal Squamous Cell …

…, M Shi, X Zhen, X Zhang, L Yang, R Zhou, S Wu - Clinical Cancer …, 2019 - AACR
Purpose: Our study aimed to investigate whether CAF (cancer-associated fibroblasts) were
involved in long noncoding RNAs (lncRNA)-regulated radioresponse in esophageal …

[HTML][HTML] CAF-secreted CXCL1 conferred radioresistance by regulating DNA damage response in a ROS-dependent manner in esophageal squamous cell carcinoma

…, J Yue, Z Jiang, R Zhou, R Xie, Y Xu, S Wu - Cell death & …, 2017 - nature.com
Five-year survival rate of esophageal squamous cell carcinoma (ESCC) patients treated
with radiotherapy is< 20%. Our study aimed to investigate whether cancer-associated …

[HTML][HTML] Shotgun transcriptome and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

…, M Loda, LF Westblade, M Cushing, S Levy, S Wu… - BioRxiv, 2020 - ncbi.nlm.nih.gov
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused
thousands of deaths worldwide, including> 18,000 in New York City (NYC) alone. The sudden …

Randomized phase II study of concurrent cisplatin/etoposide or paclitaxel/carboplatin and thoracic radiotherapy in patients with stage III non-small cell lung cancer

L Wang, S Wu, G Ou, N Bi, W Li, H Ren, J Cao, J Liang… - Lung cancer, 2012 - Elsevier
OBJECTIVE: To evaluate the activity and safety of concurrent thoracic radiotherapy (TRT)
plus weekly paclitaxel/carboplatin (PC) regimen compared with widely used cisplatin/…