Design and in vivo pharmacodynamic evaluation of nanostructured lipid carriers for parenteral delivery of artemether: Nanoject
M Joshi, S Pathak, S Sharma, V Patravale - International journal of …, 2008 - Elsevier
The objective of the present investigation was to explore the potential of nanostructured
lipid carriers (NLC) for the intravenous delivery of artemether (ARM), a poorly water-soluble …
lipid carriers (NLC) for the intravenous delivery of artemether (ARM), a poorly water-soluble …
Clotrimazole nanoemulsion for malaria chemotherapy. Part I: Preformulation studies, formulation design and physicochemical evaluation
V Borhade, S Pathak, S Sharma, V Patravale - International journal of …, 2012 - Elsevier
Clotrimazole was formulated in nanoemulsion based system with the aim of improving its
solubility and dissolution, which can further used for its preclinical evaluation. Clotrimazole …
solubility and dissolution, which can further used for its preclinical evaluation. Clotrimazole …
Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation
…, R Jain, S Patil, R Dhumal, D Tiwari, S Sharma… - Journal of …, 2010 - Elsevier
The present investigation involved preparation of hydrogel nanoparticles using a combination
of hydroxyl propyl methyl cellulose and polyvinyl pyrrolidone. The objective was to exploit …
of hydroxyl propyl methyl cellulose and polyvinyl pyrrolidone. The objective was to exploit …
Development of SMEDDS using natural lipophile: application to β-artemether delivery
SD Mandawgade, S Sharma, S Pathak… - International Journal of …, 2008 - Elsevier
The objective of the present investigation was to formulate self-microemulsifying drug delivery
systems (SMEDDS) using a novel, indigenous natural lipophile (N-LCT) as an oily phase. …
systems (SMEDDS) using a novel, indigenous natural lipophile (N-LCT) as an oily phase. …
[HTML][HTML] Malaria parasite-infected erythrocytes inhibit glucose utilization in uninfected red cells
M Mehta, HM Sonawat, S Sharma - FEBS letters, 2005 - Elsevier
The erythrocytic stages of the malaria parasite depend on anaerobic glycolysis for energy.
Using [2- 13 C]glucose and nuclear magnetic resonance, the glucose utilization rate and 2,3-…
Using [2- 13 C]glucose and nuclear magnetic resonance, the glucose utilization rate and 2,3-…
[HTML][HTML] Age-dependent sex bias in clinical malarial disease in hypoendemic regions
S Pathak, M Rege, NJ Gogtay, U Aigal, SK Sharma… - PLoS …, 2012 - journals.plos.org
Background and Objectives Experimental models show a male bias in murine malaria;
however, extant literature on biases in human clinical malaria is inconclusive. Studies in …
however, extant literature on biases in human clinical malaria is inconclusive. Studies in …
Metabolic Fingerprints of Serum, Brain, and Liver Are Distinct for Mice with Cerebral and Noncerebral Malaria: A 1H NMR Spectroscopy-Based Metabonomic Study
S Ghosh, A Sengupta, S Sharma… - Journal of proteome …, 2012 - ACS Publications
Cerebral malaria (CM) is a life-threatening disease in humans caused by Plasmodium
falciparum, leading to high mortality. Plasmodium berghei ANKA (PbA) infection in C57Bl/6 mice …
falciparum, leading to high mortality. Plasmodium berghei ANKA (PbA) infection in C57Bl/6 mice …
[HTML][HTML] Plasmodium falciparum enolase: stage-specific expression and sub-cellular localization
I Pal Bhowmick, N Kumar, S Sharma, I Coppens… - Malaria journal, 2009 - Springer
Background In an earlier study, it was observed that the vaccination with Plasmodium falciparum
enolase can confer partial protection against malaria in mice. Evidence has also build …
enolase can confer partial protection against malaria in mice. Evidence has also build …
Distinct Th1- and Th2-Type Prenatal Cytokine Responses to Plasmodium falciparum Erythrocyte Invasion Ligands
…, P Mungai, E Muchiri, J Ouma, S Sharma… - Infection and …, 2005 - Am Soc Microbiol
Prenatal immunity to Plasmodium falciparum merozoite proteins involved in erythrocyte invasion
may contribute to the partial protection against malaria that is acquired during infancy in …
may contribute to the partial protection against malaria that is acquired during infancy in …
Solid microemulsion preconcentrate (NanOsorb) of artemether for effective treatment of malaria
M Joshi, S Pathak, S Sharma, V Patravale - International journal of …, 2008 - Elsevier
A microemulsion preconcentrate was formulated on the basis of solubility of artemether (ARM)
in the various oily phases and surfactants and phase diagrams. Various solid adsorbents …
in the various oily phases and surfactants and phase diagrams. Various solid adsorbents …