[HTML][HTML] Temperature Sensing of Deep Abdominal Region in Mice by Using Over-1000 nm Near-Infrared Luminescence of Rare-Earth-Doped NaYF4 …

S Sekiyama, M Umezawa, S Kuraoka, T Ube… - Scientific reports, 2018 - nature.com
Luminescence nanothermometry has attracted much attention as a non-contact thermal
sensing technique. However, it is not widely explored for in vivo applications owing to the low …

[HTML][HTML] Biological deep temperature imaging with fluorescence lifetime of rare-earth-doped ceramics particles in the second NIR biological window

T Chihara, M Umezawa, K Miyata, S Sekiyama… - Scientific reports, 2019 - nature.com
Contactless thermal imaging generally relies on mid-infrared cameras and fluorescence
imaging with temperature-sensitive phosphors. Fluorescent thermometry in the near-infrared (…

Delayed increase in near-infrared fluorescence in cultured murine cancer cells labeled with oxygen-doped single-walled carbon nanotubes

S Sekiyama, M Umezawa, Y Iizumi, T Ube, T Okazaki… - Langmuir, 2018 - ACS Publications
The labeling technique for cells with over-thousand-nanometer near-infrared (OTN-NIR)
fluorescent probes has attracted much attention for in vivo deep imaging for cell tracking and …

[HTML][HTML] Rapid increase in transparency of biological organs by matching refractive index of medium to cell membrane using phosphoric acid

M Umezawa, S Haruguchi, R Fukushima, S Sekiyama… - RSC …, 2019 - pubs.rsc.org
Tissue clearing is a fundamental challenge in biology and medicine to achieve high-resolution
optical imaging of tissues deep inside intact organs. The clearing methods reported up to …

Heat Treatment Effects for Controlling Dye Molecular States in the Hydrophobic Core of Over-1000 nm Near-Infrared (NIR-II) Fluorescent Micellar Nanoparticles

M Umezawa, H Kobayashi, K Ichihashi, S Sekiyama… - ACS …, 2022 - ACS Publications
Organic molecules that emit near-infrared (NIR) fluorescence at wavelengths above 1000
nm, also known as the second NIR (NIR-II) biological window, are expected to be applied to …

Rapid clearing of biological organs by using phosphoric acid, a hydrophilic solution with high refractive index

M Umezawa, S Haruguchi, R Fukushima, S Sekiyama… - bioRxiv, 2018 - biorxiv.org
Tissue clearing is a fundamental challenge in biology and medicine to achieve high-resolution
optical imaging of tissues deep inside intact organs. The clearing methods, reported up to …

[HTML][HTML] Visual support system for remote control by adaptive ROI selection of monitoring robot

S Samejima, K Fozilov, K Sekiyama - Robomech Journal, 2018 - Springer
A visual assistance system has become attractive as a technique to improve the efficiency
and stability of remote control. While an operator controls a working robot, another …

[PDF][PDF] Is Space-Efficient Polymorphic Gradual Typing Possible?

S OZAKI, T SEKIYAMA, A IGARASHI - webyrd.net
Gradual typing, proposed by Siek and Taha, is a way to combine static and dynamic typing
in a single programming language. Since its inception, researchers have studied techniques …

Upconversion luminescent nanostructure with ultrasmall ceramic nanoparticles coupled with rose bengal for NIR-induced photodynamic therapy

K Tezuka, M Umezawa, TI Liu, K Nomura… - ACS Applied Bio …, 2021 - ACS Publications
We designed a biodegradable hybrid nanostructure for near-infrared (NIR)-induced photodynamic
therapy (PDT) using an ultrasmall upconversion (UC) phosphor (β-NaYF 4 :Yb 3+ , Er …

EDTA functionalization of SrF2:Yb,Er nanoparticles by hydrothermal synthesis: Intense red upconversion, NIR-to-NIR emission and luminescence nanothermometry …

J Senthilselvan, S Thomas, L Anbharasi… - Journal of Materials …, 2019 - Springer
… Interestingly, Japanese researchers Shota Sekiyama et al. have investigated the
nanothermometry by exploiting the rare earth doped NaYF 4 nanoparticles for bio applications to …