Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress
Membrane integrity at the endoplasmic reticulum (ER) is tightly regulated, and its disturbance
is implicated in metabolic diseases. Using an engineered sensor that activates the …
is implicated in metabolic diseases. Using an engineered sensor that activates the …
[HTML][HTML] Genome assembly and chemogenomic profiling of National Flower of Singapore Papilionanthe Miss Joaquim 'Agnes' reveals metabolic pathways regulating …
…, ZJ Low, PN Shingate, JH Hong, SC Chong… - Communications …, 2022 - nature.com
Singapore’s National Flower, Papilionanthe (Ple.) Miss Joaquim ‘Agnes’ (PMJ) is highly
prized as a horticultural flower from the Orchidaceae family. A combination of short-read …
prized as a horticultural flower from the Orchidaceae family. A combination of short-read …
Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial
WJ Lee, K Chong, KH Ser, YC Lee, SC Chen… - Archives of …, 2011 - jamanetwork.com
Objectives To determine the efficacies of 2 weight-reducing operations on diabetic control
and the role of duodenum exclusion. Design Double-blind randomized controlled trial. Setting …
and the role of duodenum exclusion. Design Double-blind randomized controlled trial. Setting …
Comprehensive interactome analysis for the sole adenylyl cyclase Cyr1 of Candida albicans
G Zeng, SP Neo, LM Pang, J Gao, SC Chong… - Microbiology …, 2022 - Am Soc Microbiol
Cyr1, the sole adenylyl cyclase of the fungal pathogen Candida albicans , is a central
component of the cAMP/protein kinase A signaling pathway that controls the yeast-to-hypha …
component of the cAMP/protein kinase A signaling pathway that controls the yeast-to-hypha …
Predicting the glycemic response to gastric bypass surgery in patients with type 2 diabetes
JB Dixon, LM Chuang, K Chong, SC Chen… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE To find clinically meaningful preoperative predictors of diabetes remission and
conversely inadequate glycemic control after gastric bypass surgery. Predicting the …
conversely inadequate glycemic control after gastric bypass surgery. Predicting the …
Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy
WJ Lee, CY Chen, K Chong, YC Lee, SC Chen… - Surgery for Obesity and …, 2011 - Elsevier
BACKGROUND: Laparoscopic gastric bypass (GB) is reportedly more effective than laparoscopic
sleeve gastrectomy (SG) in the treatment of patients with a low body mass index and …
sleeve gastrectomy (SG) in the treatment of patients with a low body mass index and …
Laparoscopic sleeve gastrectomy for diabetes treatment in nonmorbidly obese patients: efficacy and change of insulin secretion
…, K Chong, YC Lee, SC Chen, JJ Tsou, JC Chen… - Surgery, 2010 - Elsevier
BACKGROUND: Sleeve gastrectomy is a new bariatric surgery, and many reports have
showed that patients who have undergone sleeve gastrectomy have experienced rapid …
showed that patients who have undergone sleeve gastrectomy have experienced rapid …
Laparoscopic sleeve gastrectomy versus single anastomosis (mini-) gastric bypass for the treatment of type 2 diabetes mellitus: 5-year results of a randomized trial …
WJ Lee, K Chong, YH Lin, JH Wei, SC Chen - Obesity surgery, 2014 - Springer
Background Bariatric surgery may be beneficial in mildly obese patients with poorly controlled
diabetes. The optimal procedure to achieve diabetes remission is unknown. In 2011, we …
diabetes. The optimal procedure to achieve diabetes remission is unknown. In 2011, we …
High incidence of secondary hyperparathyroidism in bariatric patients: comparing different procedures
JH Wei, WJ Lee, K Chong, YC Lee, SC Chen… - Obesity surgery, 2018 - Springer
Background Bariatric surgery is an effective therapy for morbid obesity but may reduce calcium
absorption and significantly decrease the bone mineral density. This study examined the …
absorption and significantly decrease the bone mineral density. This study examined the …
C-peptide predicts the remission of type 2 diabetes after bariatric surgery
WJ Lee, K Chong, KH Ser, JC Chen, YC Lee, SC Chen… - Obesity surgery, 2012 - Springer
Background C-peptide is a surrogate of the pancreatic beta cell mass. However, the clinical
significance of C-peptide in a diabetic patient after bariatric surgery has not been studied …
significance of C-peptide in a diabetic patient after bariatric surgery has not been studied …