Chemical synapses between axons and dendrites mediate neuronal intercellular communication.
Here, we describe a synapse between axons and primary cilia: the axo-ciliary synapse…

INTRODUCTION Neural circuits across the brain are composed of structures spanning seven
orders of magnitude in size that are assembled from thousands of distinct protein types. …

Piloerection (goosebumps) requires concerted actions of the hair follicle, the arrector pili
muscle (APM), and the sympathetic nerve, providing a model to study interactions across …

Serial-section electron microscopy such as FIB-SEM (focused ion beam scanning electron
microscopy) has become an important tool for neuroscientists to trace the trajectories and …

Metabolic coordination between neurons and astrocytes is critical for the health of the brain.
However, neuron-astrocyte coupling of lipid metabolism, particularly in response to neural …

… Illumination Microscopy experiments, Assisted with the maintenance of the transgenic
animals; Jingjing Duan, Assisted with maintenance of the transgenic animals; Shu-Hsien Sheu, …

We generated a knockout mouse for the neuronal-specific β-tubulin isoform Tubb3 to
investigate its role in nervous system formation and maintenance. Tubb3 −/− mice have no …

Motor axons in peripheral nerves have the capacity to regenerate after injury. However, full
functional motor recovery rarely occurs clinically, and this depends on the nature and …

Solvent mapping moves molecular probes, small organic molecules containing various
functional groups, around the protein surface, finds favorable positions, clusters the …

Targeting small-molecule fluorescent indicators using genetically encoded protein tags yields
new hybrid sensors for biological imaging. Optimization of such systems requires redesign …