[HTML][HTML] Myeloid-derived suppressor cells—new and exciting players in lung cancer

Z Yang, J Guo, L Weng, W Tang, S Jin… - Journal of hematology & …, 2020 - Springer
Lung cancer (LC) is the leading cause of cancer-related death worldwide due to its late
diagnosis and poor outcomes. As has been found for other types of tumors, there is increasing …

[HTML][HTML] Detection and clinical significance of circulating tumor cells in colorectal cancer

M Jiang, S Jin, J Han, T Li, J Shi, Q Zhong, W Li… - Biomarker …, 2021 - Springer
Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal
cancer (CRC). However, biopsy is an invasive method, and due to the temporal and spatial …

MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma

…, T Yuan, H Wang, S Yao, Y Zhao, Y Liu, S Jin… - Tumor …, 2017 - journals.sagepub.com
The aim of this study was to correlate matrix metalloproteinase-2 and matrix metalloproteinase-9
expression with the clinicopathological features and outcome of patients with early …

Feasibility and tolerability of sintilimab plus anlotinib as the second‐line therapy for patients with advanced biliary tract cancers: An open‐label, single‐arm, phase II …

S Jin, R Zhao, C Zhou, Q Zhong, J Shi… - … Journal of Cancer, 2023 - Wiley Online Library
Patients with biliary tract cancer (BTC) were associated with poor prognosis and limited
therapeutic options after first‐line therapy currently. In this study, we sought to evaluate the …

[HTML][HTML] Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA

K Cui, S Jin, Y Du, J Yu, H Feng, Q Fan, W Ma - Cancer Cell International, 2019 - Springer
Background Long noncoding RNA (lncRNA) has been implicated in numerous tumors, including
pancreatic cancer (PC). However, the precise cellular roles and molecular mechanisms …

[HTML][HTML] Roles of HMGB1 in regulating myeloid-derived suppressor cells in the tumor microenvironment

S Jin, Z Yang, X Hao, W Tang, W Ma, H Zong - Biomarker Research, 2020 - Springer
Myeloid-derived suppressor cells (MDSCs) are notable contributors to the immunosuppressive
tumor microenvironment (TME) and are closely associated with tumor progression; in …

Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

S Jin, L Weng, Z Li, Z Yang, L Zhu, J Shi… - Journal of Materials …, 2020 - pubs.rsc.org
Chemodynamic therapy (CDT) has been critically challenged by insufficient H2O2 in cancer
tissues and inefficient reactive oxygen species (ROS) production. Herein, we have reported …

A Quadruplex Ultrasensitive Immunoassay for Simultaneous Assessment of Human Reproductive Hormone Proteins in Multiple Biofluid Samples

Q Cai, S Jin, H Zong, L Pei, K Cao, L Qu… - Analytical …, 2023 - ACS Publications
Reproductive hormones play vital roles in reproductive health and can be used to assess a
woman’s ovarian function and diagnose diseases associated with reproductive endocrine …

[HTML][HTML] Splicing factor SF3B1K700E mutant dysregulates erythroid differentiation via aberrant alternative splicing of transcription factor TAL1

S Jin, H Su, NT Tran, J Song, SS Lu, Y Li, S Huang… - PloS one, 2017 - journals.plos.org
More than 60% of myeloid dysplasia syndrome (MDS) contains mutations in genes encoding
for splicing factors such as SF3B1, U2AF, SRSF2 and ZRSR2. Mutations in SF3B1 are …

[PDF][PDF] Methylation of dual-specificity phosphatase 4 controls cell differentiation

…, S Aluri, T Zhang, H Guo, J Xavier-Ferrucio, S Jin… - Cell reports, 2021 - cell.com
Mitogen-activated protein kinases (MAPKs) are inactivated by dual-specificity phosphatases
(DUSPs), the activities of which are tightly regulated during cell differentiation. Using …