A poly(A) tail functions in mRNA turnover and in facilitating translation as a ribonucleoprotein
complex with poly(A) binding proteins (PABPs). However, factors that associate with the …

Codon bias has been implicated as one of the major factors contributing to mRNA stability
in several model organisms. However, the molecular mechanisms of codon bias on mRNA …

A number of long noncoding RNA s (lnc RNA s) are induced in response to specific stresses
to construct membrane‐less nuclear bodies; however, their function remains poorly …

Cell fusion has a critical role in various developmental processes, immune response, tissue
homeostasis and regeneration, and possibly, in cancer. However, the signals that regulate …

Nuclear stress bodies (nSBs) are nuclear membraneless organelles formed around stress‐inducible
HSATIII architectural long noncoding RNAs (lncRNAs). nSBs repress splicing of …

Low-density lipoprotein receptor (LDLR) mRNA is unstable, but is stabilized upon extracellular
signal-regulated kinase (ERK) activation, possibly through the binding of certain proteins …

The type III-E CRISPR–Cas7-11 effector binds a CRISPR RNA (crRNA) and the putative
protease Csx29 and catalyzes crRNA-guided RNA cleavage. We report cryo–electron …

Ribosome-associated quality control (RQC) relieves stalled ribosomes and eliminates
potentially toxic nascent polypeptide chains (NCs) that can cause neurodegeneration. During …

Wnt signaling has an important role in both embryonic development and tumorigenesis. β-Catenin,
a key component of the Wnt signaling pathway, interacts with the TCF/LEF family of …

Cells can respond to stalled ribosomes by sensing ribosome collisions and employing
quality control pathways. How ribosome stalling is resolved without collisions, however, has …