User profiles for Shuwei Xie

Shuwei Xie

Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center
Verified email at unmc.edu
Cited by 375

The endocytic recycling compartment maintains cargo segregation acquired upon exit from the sorting endosome

S Xie, K Bahl, JB Reinecke… - Molecular biology of …, 2016 - Am Soc Cell Biol
The endocytic recycling compartment (ERC) is a series of perinuclear tubular and vesicular
membranes that regulates recycling to the plasma membrane. Despite evidence that cargo is …

EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole

S Xie, N Naslavsky, S Caplan - EMBO reports, 2023 - embopress.org
Primary cilia are sensory organelles that coordinate diverse signaling pathways, controlling
development and homeostasis. Progression beyond the early steps of ciliogenesis requires …

Control of mitochondrial homeostasis by endocytic regulatory proteins

T Farmer, JB Reinecke, S Xie, K Bahl… - Journal of cell …, 2017 - journals.biologists.com
Mitochondria play essential roles in cellular energy processes, including ATP production,
control of reactive oxygen species (ROS) and apoptosis. While mitochondrial function is …

[HTML][HTML] Defining the protein and lipid constituents of tubular recycling endosomes

T Farmer, S Xie, N Naslavsky, J Stöckli… - Journal of Biological …, 2021 - ASBMB
Once internalized, receptors reach the sorting endosome and are either targeted for
degradation or recycled to the plasma membrane, a process mediated at least in part by tubular …

[HTML][HTML] GRAF1 forms a complex with MICAL-L1 and EHD1 to cooperate in tubular recycling endosome vesiculation

B Cai, S Xie, S Caplan, N Naslavsky - Frontiers in cell and …, 2014 - frontiersin.org
The biogenesis of tubular recycling endosomes (TREs) and their subsequent vesiculation
after cargo-sorting has occurred, is essential for receptor and lipid recycling to the plasma …

Diacylglycerol kinases in membrane trafficking

S Xie, N Naslavsky, S Caplan - Cellular logistics, 2015 - Taylor & Francis
Diacylglycerol kinases (DGKs) belong to a family of cytosolic kinases that regulate the
phosphorylation of diacylglycerol (DAG), converting it into phosphatidic acid (PA). There are 10 …

[HTML][HTML] EHD3 protein is required for tubular recycling endosome stabilization, and an asparagine-glutamic acid residue pair within its Eps15 homology (EH) domain …

K Bahl, S Xie, G Spagnol, P Sorgen… - Journal of Biological …, 2016 - ASBMB
An elaborate network of dynamic lipid membranes, termed tubular recycling endosomes (TRE),
coordinates the process of endocytic recycling in mammalian cells. The C-terminal …

MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium

S Xie, T Farmer, N Naslavsky… - Journal of cell …, 2019 - journals.biologists.com
The endocytic protein EHD1 plays an important role in ciliogenesis by facilitating fusion of
the ciliary vesicle and removal of CP110 (also known as CCP110) from the mother centriole, …

Sucrose non-fermenting protein kinase gene UvSnf1 is required for virulence in Ustilaginoidea virens

H Wen, S Meng, S Xie, H Shi, J Qiu, N Jiang, Y Kou - Virulence, 2023 - Taylor & Francis
Rice false smut caused by Ustilaginoidea virens is becoming one of the most devastating
diseases in rice production areas in the world. Revealing U. virens potential pathogenic …

The retromer complex regulates C. elegans development and mammalian ciliogenesis

S Xie, C Dierlam, E Smith, R Duran… - Journal of cell …, 2022 - journals.biologists.com
The mammalian retromer consists of subunits VPS26 (either VPS26A or VPS26B), VPS29
and VPS35, and a loosely associated sorting nexin (SNX) heterodimer or a variety of other …