The microtubule-associated protein Tau plays a key role in the neuropathology of Alzheimer’s
disease by forming intracellular neurofibrillary tangles. Tau in the normal physiological …

The Alzheimer’s disease (AD) therapeutic research is yielding a large number of potent
molecules. The nanoparticle-based therapeutics against the protein aggregation in AD is also …

Tau aggregation and accumulation is a key event in the pathogenesis of Alzheimer’s disease.
Inhibition of Tau aggregation is therefore a potential therapeutic strategy to ameliorate the …

Alzheimer's disease (AD) is a neurodegenerative disorder caused by protein misfolding,
aggregation and accumulation in the brain. A large number of molecules are being screened …

Background Amyloid aggregate deposition is the key feature of Alzheimer’s disease. The
proteinaceous aggregates found in the afflicted brain are the intra-neuronal neurofibrillary …

Background: Alzheimer’s disease is a type of dementia denoted by progressive neuronal
death due to the accumulation of proteinaceous aggregates of Tau. Post-translational …

Background Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s
disease (AD) and a group of other related diseases collectively known as Tauopathies. In AD, …

Tau is a natively unfolded microtubule-associated protein. Tau neurofibrillary tangles are one
of the hallmarks of Alzheimer’s disease. The post-translational modifications of Tau lead to …

Background: Frontotemporal dementia and parkinsonism-linked to chromosome-17 are a
group of diseases with tau mutations leading to primary tauopathies which include progressive …

Microtubule-associated protein Tau undergoes aggregation in Alzheimer’s disease and a
group of other related diseases collectively known as Tauopathies. In AD, Tau forms …