The discovery of long non-coding RNA (lncRNA) has dramatically altered our understanding
of cancer. Here, we describe a comprehensive analysis of lncRNA alterations at …

In a genome-wide survey on somatic copy-number alterations (SCNAs) of long noncoding
RNA (lncRNA) in 2,394 tumor specimens from 12 cancer types, we found that about 21.8% of …

Genome-wide association studies (GWASs) have identified hundreds of susceptibility genes,
including shared associations across clinically distinct autoimmune diseases. We …

Disparities in cancer care have been a long-standing challenge. We estimated the genetic
ancestry of The Cancer Genome Atlas patients, and performed a pan-cancer analysis on the …

Autoimmune diseases (AIDs) are polygenic diseases affecting 7–10% of the population in
the Western Hemisphere with few effective therapies. Here, we quantify the heritability of …

EO Wilson proposed in Sociobiology that similarities between human and animal societies
reflect common mechanistic and evolutionary roots. When introduced in 1975, this …

We propose new nonparametric empirical Bayes methods for high-dimensional classification.
Our classifiers are designed to approximate the Bayes classifier in a hypothesized …

Social challenges like territorial intrusions evoke behavioral responses in widely diverging
species. Recent work has showed that evolutionary “toolkits”—genes and modules with …

Objectives To determine the incidence of postchemoradiotherapy (post-CRT) neck dissection
(ND) complications; to ascertain whether timing (<12 vs ≥12 weeks) from CRT to ND or …

Integrative genomics offers a promising approach to more powerful genetic association
studies. The hope is that combining outcome and genotype data with other types of genomic …