The mycobacterial cord factor trehalose-6, 6-dimycolate (TDM) and its synthetic analog
trehalose-6, 6-dibehenate (TDB) are potent adjuvants for Th1/Th17 vaccination that activate Syk-…

The recognition of carbohydrate moieties by cells of the innate immune system is emerging
as an essential element in antifungal immunity, but despite the number and diversity of …

Multi-protein complexes called inflammasomes have recently been identified and shown to
contribute to cell death in tissue injury. Intravenous immunoglobulin (IVIg) is an FDA-…

Oxidative stress has emerged as a key deleterious factor in brain ischemia and reperfusion.
Malfunction of the oxidative respiratory chain in mitochondria combines with the activation of …

Inflammation is an innate immune response to infection or tissue damage that is designed
to limit harm to the host, but contributes significantly to ischemic brain injury following stroke. …

Objective To characterize the changes in microglial proinflammatory M1 and antiinflammatory
M2 marker expression during epileptogenesis in the chronic pilocarpine and …

Objective Establish the prevalence of illness symptoms, poor sleep quality, poor mental health
symptoms, low energy availability and stress-recovery state in an Olympic cohort late in …

Recent findings have revealed a novel inflammatory mechanism that contributes to tissue
injury in cerebral ischemia mediated by multi-protein complexes termed inflammasomes. …

Objectives Illness can disrupt training and competition performance of athletes. Few studies
have quantified the relative contribution of the known medical, behavioural and lifestyle risk …

Plant (Secale cereale, Triticum aestivum) and animal (Eyprepocnemis plorans) meiocytes
were analyzed by indirect immunostaining with an antibody recognizing histone H3 …