Extracellular vesicles are a heterogeneous family of vesicles, generated from different
subcellular compartments and released into the extracellular space. Composed of a lipid bilayer …

Musculoskeletal chronic pain is prevalent in individuals with Alzheimer’s disease (AD);
however, it remains largely untreated in these patients, raising the possibility that pain …

Extracellular vesicles (EVs) are emerging as key players in different stages of atherosclerosis.
Here we provide evidence that EVs released by mixed aggregates of monocytes and …

Pain is a persistent symptom of Rheumatoid Arthritis, and the K/BxN serum transfer model
recapitulates both association and dissociation between pain and joint inflammation in RA. …

Background Atherosclerosis is a chronic inflammatory disease driven by macrophage
accumulation in medium and large sized arteries. Macrophage polarization and inflammation are …

Aims The cardio-protective and immuno-regulatory properties of RTP-026, a synthetic peptide
that spans the Annexin-A1 (AnxA1) N-terminal region, were tested in rat acute myocardial …

Rheumatoid arthritis-associated pain is poorly managed, often persisting when joint
inflammation is pharmacologically controlled. Comparably, in the mouse K/BxN serum-transfer …

An impairment of cardiac function is a key feature of the cardiovascular failure associated
with sepsis. Although there is some evidence that suppression of sarcoplasmic reticulum Ca 2…

Objectives: To characterize MV profiles in sepsis due to CAP or fecal peritonitis (FP) and
determine their relation to outcome. To investigate the effects of novel sepsis treatments (…

Background: Rapid and accurate new biomarkers to predict risk of cardiovascular disease (CVD)
are essential. The utility of extracellular vesicles in predicting the CVD risk is postulated…