Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals

…, FS Schenkel, G Sahana, A Govignon-Gion, S Boitard… - Nature …, 2018 - nature.com
Stature is affected by many polymorphisms of small effect in humans 1 . In contrast, variation
in dogs, even within breeds, has been suggested to be largely due to variants in a small …

[HTML][HTML] Genome-wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection

JW Kijas, JA Lenstra, B Hayes, S Boitard… - PLoS …, 2012 - journals.plos.org
Through their domestication and subsequent selection, sheep have been adapted to thrive
in a diverse range of environments. To characterise the genetic consequence of both …

Uncovering adaptation from sequence data: lessons from genome resequencing of four cattle breeds

S Boitard, M Boussaha, A Capitan, D Rocha… - Genetics, 2016 - academic.oup.com
Detecting the molecular basis of adaptation is one of the major questions in population genetics.
With the advance in sequencing technologies, nearly complete interrogation of genome-…

[HTML][HTML] Inferring population size history from large samples of genome-wide molecular data-an approximate Bayesian computation approach

S Boitard, W Rodríguez, F Jay, S Mona… - PLoS genetics, 2016 - journals.plos.org
Inferring the ancestral dynamics of effective population size is a long-standing question in
population genetics, which can now be tackled much more accurately thanks to the massive …

[HTML][HTML] Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems

KA Lê Cao, S Boitard, P Besse - BMC bioinformatics, 2011 - Springer
Background Variable selection on high throughput biological data, such as gene expression
or single nucleotide polymorphisms (SNPs), becomes inevitable to select relevant …

Detecting signatures of selection through haplotype differentiation among hierarchically structured populations

MI Fariello, S Boitard, H Naya, M SanCristobal… - Genetics, 2013 - academic.oup.com
The detection of molecular signatures of selection is one of the major concerns of modern
population genetics. A widely used strategy in this context is to compare samples from several …

[HTML][HTML] On the importance of being structured: instantaneous coalescence rates and human evolution—lessons for ancestral population size inference?

O Mazet, W Rodríguez, S Grusea, S Boitard, L Chikhi - Heredity, 2016 - nature.com
Most species are structured and influenced by processes that either increased or reduced
gene flow between populations. However, most population genetic inference methods …

Detecting selection in population trees: the Lewontin and Krakauer test extended

M Bonhomme, C Chevalet, B Servin, S Boitard… - Genetics, 2010 - academic.oup.com
Detecting genetic signatures of selection is of great interest for many research issues. Common
approaches to separate selective from neutral processes focus on the variance of F ST …

[HTML][HTML] Selection signatures in worldwide sheep populations

…, MS Cristobal, S Boitard - PloS one, 2014 - journals.plos.org
The diversity of populations in domestic species offers great opportunities to study genome
response to selection. The recently published Sheep HapMap dataset is a great example of …

[HTML][HTML] Early life microbial exposures shape the Crassostrea gigas immune system for lifelong and intergenerational disease protection

…, S Comarmond, C Chaparro, E Toulza, S Boitard… - Microbiome, 2022 - Springer
Background The interaction of organisms with their surrounding microbial communities
influences many biological processes, a notable example of which is the shaping of the immune …