User profiles for Simon D. Connell
Simon ConnellAssociate Professor of Physics, University of Leeds Verified email at leeds.ac.uk Cited by 3487 |
[HTML][HTML] PE and PS lipids synergistically enhance membrane poration by a peptide with anticancer properties
Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer properties. Its
activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer …
activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer …
[HTML][HTML] Transforming sustainable plant proteins into high performance lubricating microgels
With the resource-intensive meat industry accounting for over 50% of food-linked emissions,
plant protein consumption is an inevitable need of the hour. Despite its significance, the key …
plant protein consumption is an inevitable need of the hour. Despite its significance, the key …
The atomic force microscope as a tool for studying phase separation in lipid membranes
SD Connell, DA Smith - Molecular membrane biology, 2006 - Taylor & Francis
Atomic force microscopy has developed into a powerful tool in the study of phase separation
in lipid bilayers. Its ability to image a semi-fluid surface under buffer at nanometre lateral …
in lipid bilayers. Its ability to image a semi-fluid surface under buffer at nanometre lateral …
Redox enzymes in tethered membranes
An electrode surface is presented that enables the characterization of redox-active
membrane enzymes in a native-like environment. An ubiquinol oxidase from Escherichia coli, …
membrane enzymes in a native-like environment. An ubiquinol oxidase from Escherichia coli, …
[HTML][HTML] A fibrin biofilm covers blood clots and protects from microbial invasion
…, A Casini, JL Degen, SD Connell… - The Journal of …, 2018 - Am Soc Clin Investig
Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a characteristic
network, interact with blood cells, and initiate tissue repair. The fibrin network is porous and …
network, interact with blood cells, and initiate tissue repair. The fibrin network is porous and …
Sub‐nanometer thick gold nanosheets as highly efficient catalysts
…, PL Coletta, K Critchley, SD Connell… - Advanced …, 2019 - Wiley Online Library
2D metal nanomaterials offer exciting prospects in terms of their properties and functions.
However, the ambient aqueous synthesis of atomically‐thin, 2D metallic nanomaterials …
However, the ambient aqueous synthesis of atomically‐thin, 2D metallic nanomaterials …
Thrombin and fibrinogen γ′ impact clot structure by marked effects on intrafibrillar structure and protofibril packing
…, RA Ajjan, VC Ridger, SD Connell… - Blood, The Journal …, 2016 - ashpublications.org
Previous studies have shown effects of thrombin and fibrinogen γ′ on clot structure. However,
structural information was obtained using electron microscopy, which requires sample …
structural information was obtained using electron microscopy, which requires sample …
[HTML][HTML] Coincident molecular auxeticity and negative order parameter in a liquid crystal elastomer
D Mistry, SD Connell, SL Mickthwaite… - Nature …, 2018 - nature.com
Auxetic materials have negative Poisson’s ratios and so expand rather than contract in one
or several direction(s) perpendicular to applied extensions. The auxetics community has long …
or several direction(s) perpendicular to applied extensions. The auxetics community has long …
[HTML][HTML] Interactions between callose and cellulose revealed through the analysis of biopolymer mixtures
…, Y Helariutta, M Fuller, T Budtova, SD Connell… - Nature …, 2018 - nature.com
The properties of (1,3)-β-glucans (ie, callose) remain largely unknown despite their importance
in plant development and defence. Here we use mixtures of (1,3)-β-glucan and cellulose, …
in plant development and defence. Here we use mixtures of (1,3)-β-glucan and cellulose, …
Nanoscale mechanics of microgel particles
Microgel particles are highly tuneable materials that are useful for a wide range of industrial
applications, such as drug delivery, sensing, nanoactuation, emulsion stabilisation and use …
applications, such as drug delivery, sensing, nanoactuation, emulsion stabilisation and use …