User profiles for Simon D. Connell

Simon Connell

Associate Professor of Physics, University of Leeds
Verified email at leeds.ac.uk
Cited by 3487

[HTML][HTML] PE and PS lipids synergistically enhance membrane poration by a peptide with anticancer properties

…, A Aufderhorst-Roberts, MS Palma, SD Connell… - Biophysical …, 2015 - cell.com
Polybia-MP1 (MP1) is a bioactive host-defense peptide with known anticancer properties. Its
activity is attributed to excess serine (phosphatidylserine (PS)) on the outer leaflet of cancer …

[HTML][HTML] Transforming sustainable plant proteins into high performance lubricating microgels

…, E Liamas, R Ettelaie, SD Connell, D Dini… - Nature …, 2023 - nature.com
With the resource-intensive meat industry accounting for over 50% of food-linked emissions,
plant protein consumption is an inevitable need of the hour. Despite its significance, the key …

The atomic force microscope as a tool for studying phase separation in lipid membranes

SD Connell, DA Smith - Molecular membrane biology, 2006 - Taylor & Francis
Atomic force microscopy has developed into a powerful tool in the study of phase separation
in lipid bilayers. Its ability to image a semi-fluid surface under buffer at nanometre lateral …

Redox enzymes in tethered membranes

LJC Jeuken, SD Connell, PJF Henderson… - Journal of the …, 2006 - ACS Publications
An electrode surface is presented that enables the characterization of redox-active
membrane enzymes in a native-like environment. An ubiquinol oxidase from Escherichia coli, …

[HTML][HTML] A fibrin biofilm covers blood clots and protects from microbial invasion

…, A Casini, JL Degen, SD Connell… - The Journal of …, 2018 - Am Soc Clin Investig
Hemostasis requires conversion of fibrinogen to fibrin fibers that generate a characteristic
network, interact with blood cells, and initiate tissue repair. The fibrin network is porous and …

Sub‐nanometer thick gold nanosheets as highly efficient catalysts

…, PL Coletta, K Critchley, SD Connell… - Advanced …, 2019 - Wiley Online Library
2D metal nanomaterials offer exciting prospects in terms of their properties and functions.
However, the ambient aqueous synthesis of atomically‐thin, 2D metallic nanomaterials …

Thrombin and fibrinogen γ′ impact clot structure by marked effects on intrafibrillar structure and protofibril packing

…, RA Ajjan, VC Ridger, SD Connell… - Blood, The Journal …, 2016 - ashpublications.org
Previous studies have shown effects of thrombin and fibrinogen γ′ on clot structure. However,
structural information was obtained using electron microscopy, which requires sample …

[HTML][HTML] Coincident molecular auxeticity and negative order parameter in a liquid crystal elastomer

D Mistry, SD Connell, SL Mickthwaite… - Nature …, 2018 - nature.com
Auxetic materials have negative Poisson’s ratios and so expand rather than contract in one
or several direction(s) perpendicular to applied extensions. The auxetics community has long …

[HTML][HTML] Interactions between callose and cellulose revealed through the analysis of biopolymer mixtures

…, Y Helariutta, M Fuller, T Budtova, SD Connell… - Nature …, 2018 - nature.com
The properties of (1,3)-β-glucans (ie, callose) remain largely unknown despite their importance
in plant development and defence. Here we use mixtures of (1,3)-β-glucan and cellulose, …

Nanoscale mechanics of microgel particles

…, D Baker, RJ Foster, O Cayre, J Mattsson, SD Connell - Nanoscale, 2018 - pubs.rsc.org
Microgel particles are highly tuneable materials that are useful for a wide range of industrial
applications, such as drug delivery, sensing, nanoactuation, emulsion stabilisation and use …