User profiles for Simon Drouin

Simon Drouin

- Verified email at cnrc-nrc.gc.ca - Cited by 2230

Simon Drouin

- Verified email at etsmtl.ca - Cited by 840

A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia

…, G Boucher, P Chagnon, S Drouin… - Genes & …, 2012 - genesdev.cshlp.org
In this study, we show the high frequency of spontaneous γδ T-cell leukemia (T-ALL) occurrence
in mice with biallelic deletion of enhancer of zeste homolog 2 (Ezh2). Tumor cells show …

Oxidative stress-activated zinc cluster protein Stb5 has dual activator/repressor functions required for pentose phosphate pathway regulation and NADPH production

M Larochelle, S Drouin, F Robert… - Molecular and cellular …, 2006 - Taylor & Francis
In Saccharomyces cerevisiae, zinc cluster protein Pdr1 can form homodimers as well as
heterodimers with Pdr3 and Stb5, suggesting that different combinations of these proteins may …

[HTML][HTML] DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes

S Drouin, L Laramée, PÉ Jacques, A Forest… - PLoS …, 2010 - journals.plos.org
Histone deacetylase Rpd3 is part of two distinct complexes: the large (Rpd3L) and small (Rpd3S)
complexes. While Rpd3L targets specific promoters for gene repression, Rpd3S is …

Genomewide Location Analysis of Candida albicans Upc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance

…, O Zin Al-Abdin, P Bomme, S Saidane, S Drouin… - Eukaryotic …, 2008 - Am Soc Microbiol
Upc2p, a transcription factor of the zinc cluster family, is an important regulator of sterol
biosynthesis and azole drug resistance in Candida albicans. To better understand Upc2p …

Augmented reality in neurovascular surgery: feasibility and first uses in the operating room

M Kersten-Oertel, I Gerard, S Drouin, K Mok… - International journal of …, 2015 - Springer
Purpose The aim of this report is to present a prototype augmented reality (AR) intra-operative
brain imaging system. We present our experience of using this new neuronavigation …

IBIS: an OR ready open-source platform for image-guided neurosurgery

S Drouin, A Kochanowska, M Kersten-Oertel… - International journal of …, 2017 - Springer
Purpose Navigation systems commonly used in neurosurgery suffer from two main drawbacks:
(1) their accuracy degrades over the course of the operation and (2) they require the …

The PETALE study: Late adverse effects and biomarkers in childhood acute lymphoblastic leukemia survivors

S Marcoux, S Drouin, C Laverdière… - Pediatric blood & …, 2017 - Wiley Online Library
Background Childhood cancer survivorship issues represent an established public health
challenge. Most late adverse effects (LAEs) have been demonstrated to be time and treatment …

Quantifying attention shifts in augmented reality image‐guided neurosurgery

É Léger, S Drouin, DL Collins, T Popa… - Healthcare …, 2017 - Wiley Online Library
Image‐guided surgery (IGS) has allowed for more minimally invasive procedures, leading to
better patient outcomes, reduced risk of infection, less pain, shorter hospital stays and faster …

Transcriptome comparison of winter and spring wheat responding to low temperature

PJ Gulick, S Drouin, Z Yu, J Danyluk, G Poisson… - …, 2005 - cdnsciencepub.com
Freezing tolerance in plants is a complex trait that occurs in many plant species during growth
at low, nonfreezing temperatures, a process known as cold acclimation. This process is …

Thieno-, Furo-, and Selenopheno[3,4-c]pyrrole-4,6-dione Copolymers: Effect of the Heteroatom on the Electrooptical Properties

S Beaupre, A Pron, SH Drouin, A Najari… - …, 2012 - ACS Publications
New push–pull conjugated polymers based on furo[3,4-c]pyrrole-4,6-dione (FPD) and
selenopheno[3,4-c]pyrrole-4,6-dione (SePD) have been synthesized and compared with their …