User profiles for Simon G. Sprecher

Simon Sprecher

Professor in Neurobiology, University of Fribourg, Switzerland
Verified email at unifr.ch
Cited by 2617

Sensory determinants of behavioral dynamics in Drosophila thermotaxis

…, A Cardona, M Zlatic, SG Sprecher… - Proceedings of the …, 2015 - National Acad Sciences
Complex animal behaviors are built from dynamical relationships between sensory inputs,
neuronal activity, and motor outputs in patterns with strategic value. Connecting these …

Single cell transcriptome atlas of the Drosophila larval brain

…, GL Maier, R Bruggmann, SG Sprecher - Elife, 2019 - elifesciences.org
Cell diversity of the brain and how it is affected by starvation, remains largely unknown. Here,
we introduce a single cell transcriptome atlas of the entire Drosophila first instar larval brain…

Sensorimotor structure of Drosophila larva phototaxis

…, BL De Bivort, SG Sprecher… - Proceedings of the …, 2013 - National Acad Sciences
The avoidance of light by fly larvae is a classic paradigm for sensorimotor behavior. Here,
we use behavioral assays and video microscopy to quantify the sensorimotor structure of …

[HTML][HTML] An expression atlas of variant ionotropic glutamate receptors identifies a molecular basis of carbonation sensing

…, S Cruchet, GL Neagu-Maier, SG Sprecher… - Nature …, 2018 - nature.com
Through analysis of the Drosophila ionotropic receptors (IRs), a family of variant ionotropic
glutamate receptors, we reveal that most IRs are expressed in peripheral neuron populations …

[HTML][HTML] The monoaminergic system is a bilaterian innovation

…, G Botton-Amiot, E Rosato, SG Sprecher… - Nature …, 2023 - nature.com
Monoamines like serotonin, dopamine, and adrenaline/noradrenaline (epinephrine/norepinephrine)
act as neuromodulators in the nervous system. They play a role in complex …

Switch of rhodopsin expression in terminally differentiated Drosophila sensory neurons

SG Sprecher, C Desplan - Nature, 2008 - nature.com
Specificity of sensory neurons requires restricted expression of one sensory receptor gene
and the exclusion of all others within a given cell. In the Drosophila retina, functional identity …

Associative learning in the cnidarian Nematostella vectensis

…, P Martinez, SG Sprecher - Proceedings of the …, 2023 - National Acad Sciences
The ability to learn and form memories allows animals to adapt their behavior based on
previous experiences. Associative learning, the process through which organisms learn about …

Distinct visual pathways mediate Drosophila larval light avoidance and circadian clock entrainment

…, J Blau, C Desplan, SG Sprecher - Journal of …, 2011 - Soc Neuroscience
Visual organs perceive environmental stimuli required for rapid initiation of behaviors and
can also entrain the circadian clock. The larval eye of Drosophila is capable of both functions. …

Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry

…, A Ochoa-Espinosa, O Scholz, SG Sprecher… - Biology …, 2014 - journals.biologists.com
Protein–protein interactions are crucial for cellular homeostasis and play important roles in
the dynamic execution of biological processes. While antibodies represent a well-established …

Organization of the Drosophila larval visual circuit

…, JW Truman, M Zlatic, A Cardona, SG Sprecher - Elife, 2017 - elifesciences.org
10.7554/eLife.28387.001 Visual systems transduce, process and transmit light-dependent
environmental cues. Computation of visual features depends on photoreceptor neuron types (…