User profiles for Simon Ng
Simon NgCovant Therapeutics Verified email at covanttx.com Cited by 1541 |
[HTML][HTML] Diversity of phage-displayed libraries of peptides during panning and amplification
The amplification of phage-displayed libraries is an essential step in the selection of ligands
from these libraries. The amplification of libraries, however, decreases their diversity and …
from these libraries. The amplification of libraries, however, decreases their diversity and …
Quantifying disease progression in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) exhibits characteristic variability of onset and rate of
disease progression, with inherent clinical heterogeneity making disease quantitation difficult. …
disease progression, with inherent clinical heterogeneity making disease quantitation difficult. …
Expanding the clinical, radiological and neuropathological phenotype of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to …
NG Simon, JD Parratt, MH Barnett… - Journal of Neurology …, 2012 - jnnp.bmj.com
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to
steroids (CLIPPERS) is a recently described inflammatory disease of the CNS with a …
steroids (CLIPPERS) is a recently described inflammatory disease of the CNS with a …
Peptoids: a modular approach to drug discovery.
RJ Simon, RS Kania, RN Zuckermann… - Proceedings of the …, 1992 - National Acad Sciences
Peptoids, oligomers of N-substituted glycines, are described as a motif for the generation of
chemically diverse libraries of novel molecules. Ramachandran-type plots were calculated …
chemically diverse libraries of novel molecules. Ramachandran-type plots were calculated …
Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening
Objective: MicroRNAs (miRNAs) have been shown to offer great potential in the diagnosis of
cancer. We investigated whether plasma miRNAs could discriminate between patients with …
cancer. We investigated whether plasma miRNAs could discriminate between patients with …
Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial
…, SPY Kwok, SCW Lam, JFY Lee, RYC Yiu, SSM Ng… - The Lancet, 2004 - thelancet.com
Background Although laparoscopic resection of colorectal carcinoma improves post-operative
recovery, long-term survival and disease control are the determining factors for its …
recovery, long-term survival and disease control are the determining factors for its …
Load signature study—Part I: Basic concept, structure, and methodology
J Liang, SKK Ng, G Kendall… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Load signature is the unique consumption pattern intrinsic to each individual electrical
appliance/piece of equipment. This paper focus on building a universal platform to better …
appliance/piece of equipment. This paper focus on building a universal platform to better …
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
…, RWY Chan, YK Tong, SSM Ng… - Proceedings of the …, 2015 - National Acad Sciences
Plasma consists of DNA released from multiple tissues within the body. Using genome-wide
bisulfite sequencing of plasma DNA and deconvolution of the sequencing data with …
bisulfite sequencing of plasma DNA and deconvolution of the sequencing data with …
Comparison of the proteolytic susceptibilities of homologous L‐amino acid, D‐amino acid, and N‐substituted glycine peptide and peptoid oligomers
SM Miller, RJ Simon, S Ng… - Drug Development …, 1995 - Wiley Online Library
A series of homologous L‐amino acid, D‐amino acid, and both parallel and anti‐parallel (retro)
sequence N‐substituted glycine peptide and peptoid oligomers were prepared and …
sequence N‐substituted glycine peptide and peptoid oligomers were prepared and …
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer
H19 is an imprinted oncofetal non-coding RNA recently shown to be the precursor of miR-675.
The pathophysiological roles of H19 and its mature product miR-675 to carcinogenesis …
The pathophysiological roles of H19 and its mature product miR-675 to carcinogenesis …