Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in epilepsy, …

In this review, we (i) describe the nomenclature of Broca’s area and show how the circumscribed
definition of Broca’s area is disassociated from Broca’s aphasia, (ii) describe in detail …

Epilepsy is increasingly conceptualized as a network disorder. In this cross-sectional mega-analysis,
we integrated neuroimaging and connectome analysis to identify network …

We used voxel-based morphometry (VBM), an automatic whole-brain MR image analysis
technique, to investigate gray matter abnormalities in patients with temporal lobe epilepsy (TLE…

The objective of this study is to evaluate machine learning algorithms aimed at predicting
surgical treatment outcomes in groups of patients with temporal lobe epilepsy (TLE) using only …

The epilepsies are commonly accompanied by widespread abnormalities in cerebral white
matter. ENIGMA-Epilepsy is a large quantitative brain imaging consortium, aggregating data …

Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations, but
associations between neurobiological mechanisms and macroscale connectomics remain …

Objective Medial temporal lobe epilepsy (TLE) is the most common form of medication‐resistant
focal epilepsy in adults. Despite removal of medial temporal structures, more than one‐…

Objective There are competing explanations for persistent postoperative seizures after temporal
lobe surgery. One is that 1 or more particular subtypes of mesial temporal lobe epilepsy (…

Approximately one in every two patients with pharmacoresistant temporal lobe epilepsy will
not be rendered completely seizure-free after temporal lobe surgery. The reasons for this are …