Objective Rates of worsening and evolution to secondary progressive multiple sclerosis (MS)
may be substantially lower in actively treated patients compared to natural history studies …

White matter bundle segmentation using diffusion MRI fiber tractography has become the
method of choice to identify white matter fiber pathways in vivo in human brains. However, like …

Objective A major challenge in multiple sclerosis (MS) research is the understanding of
silent progression and Progressive MS. Using a novel method to accurately capture upper …

Although the diagnosis of dementia still is primarily based on clinical criteria, neuroimaging
is playing an increasingly important role. This is in large part due to advances in techniques …

Objective: To assess whether a videogame-like digital treatment is superior to a control in
improving processing speed in adults with multiple sclerosis (MS). Methods: Adults with MS …

Background and Objectives The timing of neurodegeneration in multiple sclerosis (MS)
remains unclear. It is critical to understand the dynamics of neuroaxonal loss if we hope to …

Background Cognitive impairment is one of the most debilitating manifestations of multiple
sclerosis. Currently, the assessment of cognition relies on a time-consuming and extensive …

The head impulse test (HIT) is nowadays recognized as the gold standard for clinical testing
of the angular vestibuloocular reflex (VOR). By imposing unpredictable, abrupt head …

Diffusion imaging is very useful for the diagnosis of sporadic Creutzfeldt-Jakob disease, but
it has limitations in tracking disease progression as mean diffusivity changes non-linearly …

Purpose Proton therapy could benefit from noninvasively gaining tumor microstructure
information, at both planning and monitoring stages. The anatomical location of brain tumors, …