Human microvesicles are key mediators of cell–cell communication. Exosomes function as
microRNA transporters, playing a crucial role in physiological and pathological processes. …

Fibro-adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal
muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis …

The regeneration of the muscle tissue relies on the capacity of the satellite stem cell (SC)
population to exit quiescence, divide asymmetrically, proliferate, and differentiate. In age-…

Radiation therapy is one of the most effective methods of tumor eradication; however, in some
forms of neuroblastoma, radiation can increase the risk of secondary neoplasms, due to …

The term micro-heterogeneity refers to non-genetic cell to cell variability observed in a bell-shaped
distribution of the expression of a trait within a population. The contribution of micro-…

Repeated mechanical stress causes injuries in the adult skeletal muscle that need to be
repaired. Although muscle regeneration is a highly efficient process, it fails in some pathological …

Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by
releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-…

The coronavirus disease 2019 (COVID-19) pandemic has caused more than 2.3 million
casualties worldwide and the lack of effective treatments is a major health concern. The …

The embryonal rhabdomyosarcoma (eRMS) is a soft tissue sarcoma commonly affecting the
head and neck, the extremities and the genitourinary tract. To contribute to revealing the cell …

Muscle regeneration is a complex process governed by the interplay between several
muscle-resident mononuclear cell populations. Following acute or chronic damage these cell …