There is increasing interest in employing shotgun sequencing, rather than amplicon sequencing,
to analyze microbiome samples. Typical projects may involve hundreds of samples and …

… Anna Lange,a Sina Beier,b Daniel H. Huson,b Raphael Parusel,a Franz Iglauer,c Julia-Stefanie
Fricka … Received 27 September 2017 Accepted 10 November 2017 Published 11 …

Background Short-read sequencing technologies have long been the work-horse of
microbiome analysis. Continuing technological advances are making the application of long-read …

Insects and mammals share evolutionary conserved innate immune responses to maintain
intestinal homeostasis. We investigated whether the larvae of the greater wax moth Galleria …

Metagenomics has become a part of the standard toolkit for scientists interested in studying
microbes in the environment. Compared to 16S rDNA sequencing, which allows coarse …

Escherichia coli represents a classical intestinal gram-negative commensal. Despite this
commensalism, different E. coli strains can mediate disparate immunogenic properties in a …

With the aim to identify potential new targets to restore antimicrobial susceptibility of
multidrug-resistant (MDR) Pseudomonas aeruginosa isolates, we generated a high-density …

Like many other Bacteroides species, Bacteroides vulgatus strain mpk, a mouse fecal isolate
which was shown to promote intestinal homeostasis, utilizes a variety of mobile elements …

Early microbiome studies focused on estimating the taxonomic composition of an assemblage
of microbes using amplicon sequencing. With improved throughput and decreased cost of …

Background Development of new pan-genome analysis tools is important, as the pangenome
of a microbial species has become an important method to define the diversity of a …