Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to
disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with …

Superhydrophobic materials are investigated extensively because of their excellent surface
properties, such as self-cleaning, oil-water separation, corrosion resistance, anti-icing, and …

Synergistic governance for reducing pollution and carbon emissions can generate savings
in policy costs and respond to ecological and environmental change pressures effectively. …

Objective To apply human factors engineering principles to improve alert interface design.
We hypothesized that incorporating human factors principles into alerts would improve …

DNA mismatch repair enzymes (for example, MSH2) maintain genomic integrity, and their
deficiency predisposes to several human cancers and to drug resistance. We found that …

Although DNA modifications play an important role in gene regulation, the underlying
mechanisms remain elusive. We developed EpiSELEX-seq to probe the sensitivity of transcription …

Objectives The objective of this study was to estimate the population pharmacokinetics of
voriconazole, to identify the factors influencing voriconazole pharmacokinetics and to identify …

To develop a universal and precise detection strategy that can be applied to water contaminants
of various sizes, we designed a particle-in-MoS 2 coated cavity structure of AAO/MoS 2 /…

Achieving synergistic control of air pollution and carbon emissions is crucial for addressing
environmental changes. This study aims to assess the synergy level of pollution and carbon …

In the present study, we prepared a SCA3 animal model by generating transgenic mice
expressing polyglutamine-expanded ataxin-3-Q79. Ataxin-3-Q79 was expressed in brain areas …