User profiles for Skander Hathroubi

Skander Hathroubi

Spartha Medical, Senior Scientist and Project Leader Head of the R&D microbiology unit
Verified email at sparthamedical.eu
Cited by 710

Helicobacter pylori biofilm formation and its potential role in pathogenesis

S Hathroubi, SL Servetas, I Windham… - Microbiology and …, 2018 - Am Soc Microbiol
Despite decades of effort, Helicobacter pylori infections remain difficult to treat. Over half of
the world's population is infected by H. pylori , which is a major cause of duodenal and gastric …

Biofilms: microbial shelters against antibiotics

S Hathroubi, MA Mekni, P Domenico… - Microbial Drug …, 2017 - liebertpub.com
Biofilms are communities of aggregated bacterial cells embedded in a self-produced extracellular
polymeric matrix. Biofilms are recalcitrant to antibiotic treatment and immune defenses …

Les biofilms bactériens: leur importance en santé animale et en santé publique

YDN Tremblay, S Hathroubi… - Canadian Journal of …, 2014 - ingentaconnect.com
Les biofilms bactériens sont des amas structurés de cellules bactériennes enrobés d’une
matrice polymérique et attachés à une surface. Le biofilm protège les bactéries et leur permet …

Bacterial biofilms: their importance in animal health and public health

YD Tremblay, S Hathroubi, M Jacques - Canadian Journal of …, 2014 - europepmc.org
Les biofilms bactériens sont des amas structurés de cellules bactériennes enrobés d’une
matrice polymérique et attachés à une surface. Le biofilm protège les bactéries et leur permet …

[HTML][HTML] Helicobacter pylori Biofilm Confers Antibiotic Tolerance in Part via A Protein-Dependent Mechanism

S Hathroubi, J Zerebinski, A Clarke, KM Ottemann - Antibiotics, 2020 - mdpi.com
Helicobacter pylori, a WHO class I carcinogen, is one of the most successful human pathogens
colonizing the stomach of over 4.4 billion of the world’s population. Antibiotic therapy …

Helicobacter pylori biofilm involves a multigene stress-biased response, including a structural role for flagella

S Hathroubi, J Zerebinski, KM Ottemann - MBio, 2018 - Am Soc Microbiol
Helicobacter pylori has an impressive ability to persist chronically in the human stomach.
Similar characteristics are associated with biofilm formation in other bacteria. The H. pylori …

The flagellar motor protein FliL forms a scaffold of circumferentially positioned rings required for stator activation

…, KL Chan, X Liu, S Hathroubi… - Proceedings of the …, 2022 - National Acad Sciences
The flagellar motor stator is an ion channel nanomachine that assembles as a ring of the
MotA 5 MotB 2 units at the flagellar base. The role of accessory proteins required for stator …

Actinobacillus pleuropneumoniae biofilms: role in pathogenicity and potential impact for vaccination development

S Hathroubi, A Loera-Muro… - Animal health …, 2018 - cambridge.org
Actinobacillus pleuropneumoniae is a Gram-negative bacterium that belongs to the family
Pasteurellaceae. It is the causative agent of porcine pleuropneumonia, a highly contagious …

[HTML][HTML] Genetic requirements and transcriptomics of Helicobacter pylori biofilm formation on abiotic and biotic surfaces

S Hathroubi, S Hu, KM Ottemann - npj Biofilms and Microbiomes, 2020 - nature.com
Biofilm growth is a widespread mechanism that protects bacteria against harsh environments,
antimicrobials, and immune responses. These types of conditions challenge chronic …

[HTML][HTML] Biofilm of Helicobacter pylori: Life Cycle, Features, and Treatment Options

Y Elshenawi, S Hu, S Hathroubi - Antibiotics, 2023 - mdpi.com
Helicobacter pylori is a gastric pathogen that infects nearly half of the global population and
is recognized as a group 1 carcinogen by the Word Health Organization. The global rise in …