Long disregarded as junk DNA or genomic dark matter, endogenous retroviruses (ERVs)
have turned out to represent important components of the antiviral immune response. These …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades most innate immune
responses but may still be vulnerable to some. Here, we systematically analyze the impact …

Although endogenous retroviruses (ERVs) are known to harbor cis-regulatory elements, their
role in modulating cellular immune responses remains poorly understood. Using an RNA-…

Accumulating evidence suggests that endogenous retroviruses (ERVs) play an important
role in the host response to infection and the development of disease. By analyzing ChIP-…

… Citation: Srinivasachar Badarinarayan S, Sauter D (2022) Not all viruses cause disease:
HERV-K(HML-2) in healthy human tissues. PLoS Biol 20(10): e3001884. https://doi.org/10.1371/journal.pbio.3001884 …

Subtype C is the most prevalent clade of human immunodeficiency virus type 1 (HIV-1)
worldwide. The reasons for this are poorly understood. Here, we demonstrate that a characteristic …

Accumulating evidence suggests that endogenous retroviruses (ERVs) play an important role
in the host response to infection and the development of disease. By combining RNA- and …

The innate immune system efficiently defends the human host against viral pathogens. Thus,
viruses evolved strategies to counteract immune activation. Here, we systematically …

The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is
an important pathogenicity factor known to interact with cellular protein kinases and other …

Accumulating evidence suggests that endogenous retroviruses (ERVs) play an important
role in the host response to infection and the development of disease. By combining RNA-and …