c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling

X Fontana, M Hristova, C Da Costa, S Patodia… - Journal of Cell …, 2012 - rupress.org
The AP-1 transcription factor c-Jun is a master regulator of the axonal response in neurons.
c-Jun also functions as a negative regulator of myelination in Schwann cells (SCs) and is …

[HTML][HTML] Role of transcription factors in peripheral nerve regeneration

S Patodia, G Raivich - Frontiers in molecular neuroscience, 2012 - frontiersin.org
Following axotomy, the activation of multiple intracellular signaling cascades causes the
expression of a cocktail of regeneration-associated transcription factors which interact with each …

The ventrolateral medulla and medullary raphe in sudden unexpected death in epilepsy

S Patodia, A Somani, M O'Hare, R Venkateswaran… - Brain, 2018 - academic.oup.com
Sudden unexpected death in epilepsy (SUDEP) is a leading cause of premature death in
patients with epilepsy. One hypothesis proposes that sudden death is mediated by post-ictal …

Neuronal c‐Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N‐terminus are moderate

CA Ruff, N Staak, S Patodia, M Kaswich… - Journal of …, 2012 - Wiley Online Library
J. Neurochem. (2012) 121, 607–618. Abstract Although neural c‐Jun is essential for
successful peripheral nerve regeneration, the cellular basis of this effect and the impact of c‐Jun …

Neuropathology findings in autonomic brain regions in SUDEP and future research directions

S Patodia, A Somani, M Thom - Autonomic Neuroscience, 2021 - Elsevier
Autonomic dysfunction is implicated from clinical, neuroimaging and experimental studies in
sudden and unexpected death in epilepsy (SUDEP). Neuropathological analysis in SUDEP …

Adenosine kinase and adenosine receptors A1R and A2AR in temporal lobe epilepsy and hippocampal sclerosis and association with risk factors for SUDEP

S Patodia, B Paradiso, M Garcia, M Ellis, B Diehl… - …, 2020 - Wiley Online Library
… sclerosis and association with risk factors for SUDEP - Patodia - 2020 - Epilepsia - Wiley
Online Library … Smriti Patodia and Beatrice Paradiso contributed equally to this study. …

Regional microglial populations in central autonomic brain regions in SUDEP

A Somani, H El‐Hachami, S Patodia, S Sisodiya… - …, 2021 - Wiley Online Library
Objective Sudden unexpected death in epilepsy (SUDEP) may arise as a result of autonomic
dysfunction during a seizure. The central autonomic networks (CANs) modulate brainstem …

MRI and pathology correlations in the medulla in sudden unexpected death in epilepsy (SUDEP): a postmortem study

S Patodia, M Tachrount, A Somani… - Neuropathology and …, 2021 - Wiley Online Library
Aims Sudden unexpected death in epilepsy (SUDEP) likely arises as a result of autonomic
dysfunction around the time of a seizure. In vivo MRI studies report volume reduction in the …

Cortical neuronal hypertrophy and mTOR pathway activation in CAN regions in SUDEP

S Patodia, YM Lim, F Chung, I Stylianou… - …, 2022 - Wiley Online Library
Objectives Dysfunctional connectivity and preexisting structural abnormalities of central
autonomic network (CAN) regions have been shown on magnetic resonance imaging (MRI) in …

Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP

S Patodia, A Somani, J Liu, A Cattaneo… - Brain …, 2022 - Wiley Online Library
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with
serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP. …