The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

…, M Nõukas, D Perro, E Sliz, M Sobalska-Kwapis… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis

…, E Reszka, D Samotij, M Sobalska-Kwapis… - … in Dermatology and …, 2020 - termedia.pl
Psoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors
regulating gene expression play a key role. In the “genomic era”, genome-wide association …

Pathogenesis of psoriasis in the “omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis in psoriasis

…, R Słominski, M Sobalska-Kwapis… - … in Dermatology and …, 2020 - termedia.pl
Psoriasis is a systemic disease that is strictly connected with metabolic disorders (insulin
resistance, atherogenic dyslipidemia, arterial hypertension, and cardiovascular diseases). It …

Pathogenesis of psoriasis in the “omic” era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances

…, R Słomiński, M Sobalska-Kwapis… - … in Dermatology and …, 2020 - termedia.pl
Psoriasis is a common, chronic, inflammatory, immune-mediated skin disease affecting
about 2% of the world’s population. According to current knowledge, psoriasis is a complex …

[HTML][HTML] High resolution melting (HRM) for high-throughput genotyping—limitations and caveats in practical case studies

M Słomka, M Sobalska-Kwapis, M Wachulec… - International journal of …, 2017 - mdpi.com
High resolution melting (HRM) is a convenient method for gene scanning as well as genotyping
of individual and multiple single nucleotide polymorphisms (SNPs). This rapid, simple, …

Investigating the impact of age-depended hair colour darkening during childhood on DNA-based hair colour prediction with the HIrisPlex system

…, E Żądzińska, I Rosset, M Sobalska-Kwapis… - Forensic Science …, 2018 - Elsevier
Predictive DNA analysis of externally visible characteristics exerts an increasing influence on
contemporary forensic and anthropological investigations, with pigmentation traits currently …

[HTML][HTML] Identification of novel molecular markers of human Th17 cells

…, M Krawczyk, M Sobalska-Kwapis… - Cells, 2020 - mdpi.com
Th17 cells are important players in host defense against pathogens such as Staphylococcus
aureus, Candida albicans, and Bacillus anthracis. Th17 cell-mediated inflammation, under …

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

…, MG Stuart, M Sally, S Yadav, SJ Andrew, SK Marta… - BioRxiv, 2018 - biorxiv.org
Endometriosis is a common complex inflammatory condition characterised by the presence
of endometrium-like tissue outside the uterus, mainly in the pelvic area. It is associated with …

[HTML][HTML] Assessment of the potential role of selected single nucleotide polymorphisms (SNPs) of genes related to the functioning of regulatory T cells in the …

…, B Nedoszytko, M Sobalska-Kwapis… - International Journal of …, 2023 - mdpi.com
Recent studies have indicated a key role of the impaired suppressive capacity of regulatory
T cells (Tregs) in psoriasis (PsO) pathogenesis. However, the genetic background of Treg …

[HTML][HTML] The analysis of a genome-wide association study (GWAS) of overweight and obesity in psoriasis

A Kisielnicka, M Sobalska-Kwapis… - International Journal of …, 2022 - mdpi.com
There is evidence that the concomitance of psoriasis and obesity may originate from the
interplay between multiple genetic pathways and involve gene–gene interactions. The aim of …