Flies, like all animals, need to find suitable and safe food. Because the principal food source
for Drosophila melanogaster is yeast growing on fermenting fruit, flies need to distinguish …

In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription
hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. …

Intraspecific olfactory signals known as pheromones play important roles in insect mating
systems. In the model Drosophila melanogaster, a key part of the pheromone-detecting system …

Olfactory glomeruli are morphologically conserved spherical compartments of the olfactory
system, distinguishable solely by their chemosensory repertoire, anatomical position, and …

The hypoxia-inducible factor (HIF) is a heterodimeric transcription factor composed of a
constitutively expressed HIF-β subunit and an oxygen-regulated HIF-α subunit. We have …

Divergent populations across different environments are exposed to critical sensory information
related to locating a host or mate, as well as avoiding predators and pathogens. These …

Insect odorant receptors (ORs) have a unique design of heterodimers formed by an olfactory
receptor protein and the ion channel Orco. Heterologously expressed insect ORs are …

Insects possess one of the most exquisitely sensitive olfactory systems in the animal
kingdom, consisting of three different types of chemosensory receptors: ionotropic glutamate-like …

Communication mechanisms underlying the sexual isolation of species are poorly understood.
Using four subspecies of Drosophila mojavensis as a model, we identify two behaviorally …

Insects detect volatile chemicals using antennae, which house a vast variety of olfactory
sensory neurons (OSNs) that innervate hair-like structures called sensilla where odor detection …