Decoding immunogenic cell death from a dendritic cell perspective

S Janssens, S Rennen, P Agostinis - Immunological Reviews, 2024 - Wiley Online Library
Dendritic cells (DCs) are myeloid cells bridging the innate and adaptive immune system. By
cross‐presenting tumor‐associated antigens (TAAs) liberated upon spontaneous or therapy‐…

LXR signaling controls homeostatic dendritic cell maturation

V Bosteels, S Maréchal, C De Nolf, S Rennen… - Science …, 2023 - science.org
Dendritic cells (DCs) mature in an immunogenic or tolerogenic manner depending on the
context in which an antigen is perceived, preserving the balance between immunity and …

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

A Martens, D Priem, E Hoste, J Vetters, S Rennen… - Nature …, 2020 - nature.com
Protein ubiquitination regulates protein stability and modulates the composition of signaling
complexes. A20 is a negative regulator of inflammatory signaling, but the molecular …

The UPR sensor IRE1α promotes dendritic cell responses to control Toxoplasma gondii infection

…, V Bosteels, E Hoffmann, S Chehade, S Rennen… - EMBO …, 2021 - embopress.org
The unfolded protein response (UPR) has emerged as a central regulator of immune cell
responses in several pathologic contexts including infections. However, how intracellular …

[PDF][PDF] Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection

J Vetters, M van Helden, C De Nolf, S Rennen… - iScience, 2023 - cell.com
The unfolded protein response (UPR) aims to restore ER homeostasis under conditions of
high protein folding load, a function primarily serving secretory cells. Additional, non-…

[HTML][HTML] Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity

F Flores-Santibañez, S Rennen, D Fernandez… - Frontiers in …, 2023 - frontiersin.org
In cancer, activation of the IRE1/XBP1s axis of the unfolded protein response (UPR) promotes
immunosuppression and tumor growth, by acting in cancer cells and tumor infiltrating …

Natural Killer Cell Proliferation Requires Canonical IRE1 Function During Viral Infection

J Vetters, M van Helden, C De Nolf, S Rennen… - Available at SSRN … - papers.ssrn.com
The unfolded protein response (UPR) aims to restore ER homeostasis under conditions of
high protein folding load, a function primarily serving secretory cells. Additional, non-…

[PDF][PDF] Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity

…, F Osorio, S Janssens, F Flores-Santibañez, S Rennen… - 2023 - backoffice.biblio.ugent.be
Dendritic cells (DCs) are major coordinators of antitumor immunity. A crucial arm of this
response relies on effective activation of tumor specific cytotoxic CD8+ T cells endowed with the …

[PDF][PDF] Study of the role of type I interferons in TNF-mediated inflammation

L Grine - 2014 - biblio.ugent.be
… ik leerde direct dat ik moest rennen door de gangen om je bij te … zijn super :v) Filip en Sofie
L, exvuclisersu Het was super om … En Sofie L, al is het nog even, ook niet vergeten mij uit te …

[BOOK][B] Programm

BDD Trier - 1950 - treviris.de
… • Nach den Rennen zügig wenden und am Ufer Konz bis zur Höhe des Startbereichs zurück
… • Nach den Rennen zügig wenden und am Ufer Konz bis zur Höhe des Startbereichs zurück …