The genetic architecture of the human cerebral cortex

…, TW Mühleisen, B Müller-Myhsok, P Najt, S Nakahara… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …

[PDF][PDF] Activity-dependent proteolytic cleavage of neuroligin-1

K Suzuki, Y Hayashi, S Nakahara, H Kumazaki, J Prox… - Neuron, 2012 - cell.com
Neuroligin (NLG), a postsynaptic adhesion molecule, is involved in the formation of synapses
by binding to a cognate presynaptic ligand, neurexin. Here we report that neuroligin-1 (…

Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies

S Nakahara, M Matsumoto… - …, 2018 - Wiley Online Library
Aim The hippocampus is considered a key region in schizophrenia pathophysiology, but the
nature of hippocampal subregion abnormalities and how they contribute to disease …

[HTML][HTML] Hippocampal pathophysiology: commonality shared by temporal lobe epilepsy and psychiatric disorders

S Nakahara, M Adachi, H Ito, M Matsumoto… - Neuroscience …, 2018 - hindawi.com
Accumulating evidence points to the association of epilepsy, particularly, temporal lobe
epilepsy (TLE), with psychiatric disorders, such as schizophrenia. Among these illnesses, the …

Dentate gyrus volume deficit in schizophrenia

S Nakahara, JA Turner, VD Calhoun, KO Lim… - Psychological …, 2020 - cambridge.org
BackgroundSchizophrenia is associated with robust hippocampal volume deficits but subregion
volume deficits, their associations with cognition, and contributing genes remain to be …

Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia

S Nakahara, S Medland, JA Turner, VD Calhoun… - Schizophrenia …, 2018 - Elsevier
This study assessed genetic contributions to six cognitive domains, identified by the MATRICS
Cognitive Consensus Battery as relevant for schizophrenia, cognition-enhancing, clinical …

The ratio of 'deleted in colorectal cancer'to'uncoordinated-5A 'netrin-1 receptors on the growth cone regulates mossy fibre directionality

R Muramatsu, S Nakahara, J Ichikawa, K Watanabe… - Brain, 2010 - academic.oup.com
Proper axonal targeting is fundamental to the establishment of functional neural circuits. The
hippocampal mossy fibres normally project towards the CA3 region. In the hippocampi of …

Repulsive guidance molecule a regulates hippocampal mossy fiber branching in vitro

K Shibata, S Nakahara, E Shimizu, T Yamashita… - …, 2013 - journals.lww.com
… *Kazuki Shibata and Soichiro Nakahara contributed equally to the writing of this article. …
Nakahara S, Tamura M, Matsuki N, Koyama R.Neuronal hyperactivity sustains the basal …

Auditory oddball hypoactivation in schizophrenia

S Nakahara, AG Male, JA Turner, VD Calhoun… - Psychiatry Research …, 2023 - Elsevier
Individuals with schizophrenia (SZ) show aberrant activations, assessed via functional
magnetic resonance imaging (fMRI), during auditory oddball tasks. However, associations with …

Mossy fiber mis-pathfinding and semaphorin reduction in the hippocampus of α-CaMKII hKO mice

S Nakahara, S Miyake, K Tajinda, H Ito - Neuroscience Letters, 2015 - Elsevier
Recent evidence indicates that alpha-isoform of calcium/calmodulin-dependent protein
kinase II (α-CaMKII) deficiency in adult mice induces phenotypic immaturity of dentate granule …