The genetic architecture of the human cerebral cortex
…, TW Mühleisen, B Müller-Myhsok, P Najt, S Nakahara… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …
Variations in human cortical surface area and thickness are associated with neurological, …
[PDF][PDF] Activity-dependent proteolytic cleavage of neuroligin-1
K Suzuki, Y Hayashi, S Nakahara, H Kumazaki, J Prox… - Neuron, 2012 - cell.com
Neuroligin (NLG), a postsynaptic adhesion molecule, is involved in the formation of synapses
by binding to a cognate presynaptic ligand, neurexin. Here we report that neuroligin-1 (…
by binding to a cognate presynaptic ligand, neurexin. Here we report that neuroligin-1 (…
Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies
S Nakahara, M Matsumoto… - …, 2018 - Wiley Online Library
Aim The hippocampus is considered a key region in schizophrenia pathophysiology, but the
nature of hippocampal subregion abnormalities and how they contribute to disease …
nature of hippocampal subregion abnormalities and how they contribute to disease …
[HTML][HTML] Hippocampal pathophysiology: commonality shared by temporal lobe epilepsy and psychiatric disorders
S Nakahara, M Adachi, H Ito, M Matsumoto… - Neuroscience …, 2018 - hindawi.com
Accumulating evidence points to the association of epilepsy, particularly, temporal lobe
epilepsy (TLE), with psychiatric disorders, such as schizophrenia. Among these illnesses, the …
epilepsy (TLE), with psychiatric disorders, such as schizophrenia. Among these illnesses, the …
Dentate gyrus volume deficit in schizophrenia
BackgroundSchizophrenia is associated with robust hippocampal volume deficits but subregion
volume deficits, their associations with cognition, and contributing genes remain to be …
volume deficits, their associations with cognition, and contributing genes remain to be …
Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia
This study assessed genetic contributions to six cognitive domains, identified by the MATRICS
Cognitive Consensus Battery as relevant for schizophrenia, cognition-enhancing, clinical …
Cognitive Consensus Battery as relevant for schizophrenia, cognition-enhancing, clinical …
The ratio of 'deleted in colorectal cancer'to'uncoordinated-5A 'netrin-1 receptors on the growth cone regulates mossy fibre directionality
R Muramatsu, S Nakahara, J Ichikawa, K Watanabe… - Brain, 2010 - academic.oup.com
Proper axonal targeting is fundamental to the establishment of functional neural circuits. The
hippocampal mossy fibres normally project towards the CA3 region. In the hippocampi of …
hippocampal mossy fibres normally project towards the CA3 region. In the hippocampi of …
Repulsive guidance molecule a regulates hippocampal mossy fiber branching in vitro
K Shibata, S Nakahara, E Shimizu, T Yamashita… - …, 2013 - journals.lww.com
… *Kazuki Shibata and Soichiro Nakahara contributed equally to the writing of this article. …
Nakahara S, Tamura M, Matsuki N, Koyama R.Neuronal hyperactivity sustains the basal …
Nakahara S, Tamura M, Matsuki N, Koyama R.Neuronal hyperactivity sustains the basal …
Auditory oddball hypoactivation in schizophrenia
Individuals with schizophrenia (SZ) show aberrant activations, assessed via functional
magnetic resonance imaging (fMRI), during auditory oddball tasks. However, associations with …
magnetic resonance imaging (fMRI), during auditory oddball tasks. However, associations with …
Mossy fiber mis-pathfinding and semaphorin reduction in the hippocampus of α-CaMKII hKO mice
Recent evidence indicates that alpha-isoform of calcium/calmodulin-dependent protein
kinase II (α-CaMKII) deficiency in adult mice induces phenotypic immaturity of dentate granule …
kinase II (α-CaMKII) deficiency in adult mice induces phenotypic immaturity of dentate granule …